Genomic diversity and admixture patterns among six Chinese indigenous cattle breeds in Yunnan

OBJECTIVE: Yunnan is not only a frontier zone that connects China with South and Southeast Asia, but also represents an admixture zone between taurine (Bos taurus) and zebu (Bos indicus) cattle. The purpose of this study is to understand the level of genomic diversity and the extent of admixture in...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Asian-Australasian journal of animal sciences. - 1998. - 32(2019), 8 vom: 01. Aug., Seite 1069-1076
1. Verfasser: Li, Rong (VerfasserIn)
Weitere Verfasser: Li, Chunqing, Chen, Hongyu, Liu, Xuehong, Xiao, Heng, Chen, Shanyuan
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2019
Zugriff auf das übergeordnete Werk:Asian-Australasian journal of animal sciences
Schlagworte:Journal Article Bos indicus Bos taurus Heterozygosity Population Structure Single Nucleotide Polymorphisms
LEADER 01000naa a22002652 4500
001 NLM293701806
003 DE-627
005 20231225075904.0
007 cr uuu---uuuuu
008 231225s2019 xx |||||o 00| ||eng c
024 7 |a 10.5713/ajas.18.0605  |2 doi 
028 5 2 |a pubmed24n0978.xml 
035 |a (DE-627)NLM293701806 
035 |a (NLM)30744361 
040 |a DE-627  |b ger  |c DE-627  |e rakwb 
041 |a eng 
100 1 |a Li, Rong  |e verfasserin  |4 aut 
245 1 0 |a Genomic diversity and admixture patterns among six Chinese indigenous cattle breeds in Yunnan 
264 1 |c 2019 
336 |a Text  |b txt  |2 rdacontent 
337 |a ƒaComputermedien  |b c  |2 rdamedia 
338 |a ƒa Online-Ressource  |b cr  |2 rdacarrier 
500 |a Date Revised 30.09.2020 
500 |a published: Print-Electronic 
500 |a Citation Status PubMed-not-MEDLINE 
520 |a OBJECTIVE: Yunnan is not only a frontier zone that connects China with South and Southeast Asia, but also represents an admixture zone between taurine (Bos taurus) and zebu (Bos indicus) cattle. The purpose of this study is to understand the level of genomic diversity and the extent of admixture in each Yunnan native cattle breed 
520 |a METHODS: All 120 individuals were genotyped using Illumina BovineHD BeadChip (777,962 single nucleotide polymorphisms [SNPs]). Quality control and genomic diversity indexes were calculated using PLINK software. The principal component analysis (PCA) was assessed using SMARTPCA program implemented in EIGENSOFT software. The ADMIXTURE software was used to reveal admixture patterns among breeds 
520 |a RESULTS: A total of 604,630 SNPs was obtained after quality control procedures. Among six breeds, the highest level of mean heterozygosity was found in Zhaotong cattle from Northeastern Yunnan, whereas the lowest level of heterozygosity was detected in Dehong humped cattle from Western Yunnan. The PCA based on a pruned dataset of 233,788 SNPs clearly separated Dehong humped cattle (supposed to be a pure zebu breed) from other five breeds. The admixture analysis further revealed two clusters (K = 2 with the lowest cross validation error), corresponding to taurine and zebu cattle lineages. All six breeds except for Dehong humped cattle showed different degrees of admixture between taurine and zebu cattle. As expected, Dehong humped cattle showed no signature of taurine cattle influence 
520 |a CONCLUSION: Overall, considerable genomic diversity was found in six Yunnan native cattle breeds except for Dehong humped cattle from Western Yunnan. Dehong humped cattle is a pure zebu breed, while other five breeds had admixed origins with different extents of admixture between taurine and zebu cattle. Such admixture by crossbreeding between zebu and taurine cattle facilitated the spread of zebu cattle from tropical and subtropical regions to other highland regions in Yunnan 
650 4 |a Journal Article 
650 4 |a Bos indicus 
650 4 |a Bos taurus 
650 4 |a Heterozygosity 
650 4 |a Population Structure 
650 4 |a Single Nucleotide Polymorphisms 
700 1 |a Li, Chunqing  |e verfasserin  |4 aut 
700 1 |a Chen, Hongyu  |e verfasserin  |4 aut 
700 1 |a Liu, Xuehong  |e verfasserin  |4 aut 
700 1 |a Xiao, Heng  |e verfasserin  |4 aut 
700 1 |a Chen, Shanyuan  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Asian-Australasian journal of animal sciences  |d 1998  |g 32(2019), 8 vom: 01. Aug., Seite 1069-1076  |w (DE-627)NLM098195883  |x 1011-2367  |7 nnns 
773 1 8 |g volume:32  |g year:2019  |g number:8  |g day:01  |g month:08  |g pages:1069-1076 
856 4 0 |u http://dx.doi.org/10.5713/ajas.18.0605  |3 Volltext 
912 |a GBV_USEFLAG_A 
912 |a SYSFLAG_A 
912 |a GBV_NLM 
912 |a GBV_ILN_350 
951 |a AR 
952 |d 32  |j 2019  |e 8  |b 01  |c 08  |h 1069-1076