RNA editing in plants : A comprehensive survey of bioinformatics tools and databases

Copyright © 2019. Published by Elsevier Masson SAS.

Bibliographische Detailangaben
Veröffentlicht in:Plant physiology and biochemistry : PPB. - 1991. - 137(2019) vom: 01. Apr., Seite 53-61
1. Verfasser: Lo Giudice, Claudio (VerfasserIn)
Weitere Verfasser: Hernández, Irene, Ceci, Luigi R, Pesole, Graziano, Picardi, Ernesto
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2019
Zugriff auf das übergeordnete Werk:Plant physiology and biochemistry : PPB
Schlagworte:Journal Article Review C-To-U change Chloroplast Database Mitochondrion Organelle RNA editing RNA, Plant
Beschreibung
Zusammenfassung:Copyright © 2019. Published by Elsevier Masson SAS.
RNA editing is a widespread epitranscriptomic mechanism by which primary RNAs are specifically modified through insertions/deletions or nucleotide substitutions. In plants, RNA editing occurs in organelles (plastids and mitochondria), involves the cytosine to uridine modification (rarely uridine to cytosine) within protein-coding and non-protein-coding regions of RNAs and affects organelle biogenesis, adaptation to environmental changes and signal transduction. High-throughput sequencing technologies have dramatically improved the detection of RNA editing sites at genomic scale. Consequently, different bioinformatics resources have been released to discovery and/or collect novel events. Here, we review and describe the state-of-the-art bioinformatics tools devoted to the characterization of RNA editing in plant organelles with the aim to improve our knowledge about this fascinating but yet under investigated process
Beschreibung:Date Completed 08.03.2019
Date Revised 30.09.2020
published: Print-Electronic
Citation Status MEDLINE
ISSN:1873-2690
DOI:10.1016/j.plaphy.2019.02.001