RNA editing in plants : A comprehensive survey of bioinformatics tools and databases
Copyright © 2019. Published by Elsevier Masson SAS.
Veröffentlicht in: | Plant physiology and biochemistry : PPB. - 1991. - 137(2019) vom: 01. Apr., Seite 53-61 |
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1. Verfasser: | |
Weitere Verfasser: | , , , |
Format: | Online-Aufsatz |
Sprache: | English |
Veröffentlicht: |
2019
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Zugriff auf das übergeordnete Werk: | Plant physiology and biochemistry : PPB |
Schlagworte: | Journal Article Review C-To-U change Chloroplast Database Mitochondrion Organelle RNA editing RNA, Plant |
Zusammenfassung: | Copyright © 2019. Published by Elsevier Masson SAS. RNA editing is a widespread epitranscriptomic mechanism by which primary RNAs are specifically modified through insertions/deletions or nucleotide substitutions. In plants, RNA editing occurs in organelles (plastids and mitochondria), involves the cytosine to uridine modification (rarely uridine to cytosine) within protein-coding and non-protein-coding regions of RNAs and affects organelle biogenesis, adaptation to environmental changes and signal transduction. High-throughput sequencing technologies have dramatically improved the detection of RNA editing sites at genomic scale. Consequently, different bioinformatics resources have been released to discovery and/or collect novel events. Here, we review and describe the state-of-the-art bioinformatics tools devoted to the characterization of RNA editing in plant organelles with the aim to improve our knowledge about this fascinating but yet under investigated process |
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Beschreibung: | Date Completed 08.03.2019 Date Revised 30.09.2020 published: Print-Electronic Citation Status MEDLINE |
ISSN: | 1873-2690 |
DOI: | 10.1016/j.plaphy.2019.02.001 |