Interbreed variation of biomarkers of lipid and glucose metabolism in dogs

Interbreed variation of biomarkers of lipid and glucose metabolism in dogs

© 2018 American Society for Veterinary Clinical Pathology.

Bibliographische Detailangaben
Veröffentlicht in:Veterinary clinical pathology. - 1975. - 47(2018), 4 vom: 17. Dez., Seite 582-588
1. Verfasser: Gomez-Fernandez-Blanco, Carlos (VerfasserIn)
Weitere Verfasser: Peeters, Dominique, Moyse, Evelyne, Farnir, Frédéric, Höglund, Katja, Gouni, Vassiliki, Wiberg, Maria, Lundgren Willesen, Jakob, Hanås, Sofia, McEntee, Kathleen, Tiret, Laurent, Häggström, Jens, Lohi, Hannes, Chetboul, Valérie, Fredholm, Merete, Seppälä, Eija H, Lequarré, Anne-Sophie, Merveille, Anne-Christine
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2018
Zugriff auf das übergeordnete Werk:Veterinary clinical pathology
Schlagworte:Journal Article Canine RI cholesterol decision limits fructosamine insulin metabolic syndrome Biomarkers Blood Glucose Fatty Acids, Nonesterified mehr... Insulin Triglycerides Fructosamine 4429-04-3 C-Reactive Protein 9007-41-4 Cholesterol 97C5T2UQ7J Glucose IY9XDZ35W2
Beschreibung
Zusammenfassung:© 2018 American Society for Veterinary Clinical Pathology.
BACKGROUND: Markers of lipid and glucose metabolism are used in both clinical practice and research. Detection of abnormal laboratory results often relies on species-specific reference intervals, but interbreed variation can also affect data interpretation
OBJECTIVES: The purpose of the present study was to compare concentrations of selected biochemical variables among different dog breeds
METHODS: We analyzed a database containing information on biochemical variables from 534 dogs belonging to nine different breeds. All dogs were confirmed to be healthy based on history, physical examination, and ancillary tests. Concentrations of glucose, fructosamine, insulin, cholesterol, triglycerides, fatty acids, and C-reactive protein were compared using the nonparametric Kruskal-Wallis and Dunn's tests
RESULTS: All variables tested showed significant interbreed differences, although all breeds remained within the previously established RIs for dogs. Fructosamine, insulin, and cholesterol showed a wide interbreed variation that could affect the interpretation of results
CONCLUSIONS: Breed is an important factor to consider when assessing energy metabolism in dogs, especially for markers like fructosamine, insulin, and cholesterol, which vary considerably among breeds
Beschreibung:Date Completed 17.01.2019
Date Revised 17.01.2019
published: Print-Electronic
Citation Status MEDLINE
ISSN:1939-165X
DOI:10.1111/vcp.12673