Lipidic Mesophase-Embedded Palladium Nanoparticles : Synthesis and Tunable Catalysts in Suzuki-Miyaura Cross-Coupling Reactions
Lipidic cubic phases (LCPs) can reduce Pd2+ salts to palladium nanoparticles (PdNPs) of ∼5 nm size in their confined water channels under mild conditions. The resulting PdNP-containing LCPs were used as nanoreactor scaffolds to catalyze Suzuki-Miyaura cross-coupling reactions in the aqueous channels...
| Veröffentlicht in: | Langmuir : the ACS journal of surfaces and colloids. - 1992. - 35(2019), 1 vom: 08. Jan., Seite 120-127 |
|---|---|
| 1. Verfasser: | |
| Weitere Verfasser: | , , , , , , |
| Format: | Online-Aufsatz |
| Sprache: | English |
| Veröffentlicht: |
2019
|
| Zugriff auf das übergeordnete Werk: | Langmuir : the ACS journal of surfaces and colloids |
| Schlagworte: | Journal Article Research Support, Non-U.S. Gov't |
| Zusammenfassung: | Lipidic cubic phases (LCPs) can reduce Pd2+ salts to palladium nanoparticles (PdNPs) of ∼5 nm size in their confined water channels under mild conditions. The resulting PdNP-containing LCPs were used as nanoreactor scaffolds to catalyze Suzuki-Miyaura cross-coupling reactions in the aqueous channels of the mesophase. To turn on catalysis, PdNP-containing LCPs were activated by swelling the aqueous channels of the lipidic framework, thereby enabling diffusion of the water-soluble substrates to the catalysts. The mesophases play a threefold role: they act as reducing agents for Pd2+, as limiting templates for their growth, and as support. The system was characterized and investigated by small-angle X-ray scattering (SAXS), cryo-transmission electron microscopy, dynamic light scattering, and nuclear magnetic resonance. Bulk LCPs and three dispersed palladium/lipid hybrid nanoparticle types were applied in the catalysis. The latter-liposomes, hexosomes, and cubosomes-can be obtained by design through combination of lipids and additives. The Suzuki-Miyaura cross-coupling of 5-iodo-2'-deoxyuridine and phenylboronic acid was used as a model reaction to study these systems. Bulk Pd-LCPs deliver the Suzuki-Miyaura product in 24 h in conversions up to 98% at room temperature, whereas with palladium/lipid dispersions at 40 °C, 68% of the starting material was transformed to the product after 72 h |
|---|---|
| Beschreibung: | Date Revised 20.11.2019 published: Print-Electronic Citation Status PubMed-not-MEDLINE |
| ISSN: | 1520-5827 |
| DOI: | 10.1021/acs.langmuir.8b02905 |