Statistical correction for functional metagenomic profiling of a microbial community with short NGS reads
By sequence homology search, the list of all the functions found and the counts of reads being aligned to them present the functional profile of a metagenomic sample. However, a significant obstacle has been observed in this approach due to the short read length associated with many next generation...
| Veröffentlicht in: | Journal of applied statistics. - 1991. - 45(2018), 14 vom: 01., Seite 2521-2535 |
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| Format: | Online-Aufsatz |
| Sprache: | English |
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2018
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| Zugriff auf das übergeordnete Werk: | Journal of applied statistics |
| Schlagworte: | Journal Article Primary 62F10 conservation bias functional profiling length bias metagenomics secondary 62P10 short reads |
| Online verfügbar |
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