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|a 10.3760/cma.j.issn.0578-1310.2018.11.013
|2 doi
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|a chi
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| 100 |
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|a Tang, L J
|e verfasserin
|4 aut
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| 245 |
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|a Effect of enteral nutrition on accidental upper gastrointestinal injury in children
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|c 2018
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
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|a ƒa Online-Ressource
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|a Date Completed 01.04.2019
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|a Date Revised 01.04.2019
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|a published: Print
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|a Citation Status MEDLINE
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|a Objective: To evaluate the effectiveness of enteral nutrition in children with accidental upper gastrointestinal injury. Methods: The medical records of 128 patients with mechanical or chemical gastrointestinal mucosal injury, who were hospitalized in Department of Gastroenterology, Children's Hospital of Zhejiang University School of Medicine from January 1, 2011 to December 30, 2017, were collected. All cases were treated with enteral nutrition. The clinical features and etiologies were retrospectively analyzed. Weight-for-age Z score and lab findings including white blood cells, C-reactive protein, neutrophils, albumin, prealbumin, urea nitrogen and hemoglobin before and after treatment were extracted. The clinical characteristics, the duration of enteral nutrition and gastrointestinal mucosal healing between different etiologies were further analyzed. Normal distribution variables and categorized variables were compared with t test and χ(2) test respectively, and abnormal distribution data was compared with Wilcoxon test. Results: Among all the cases, 77 were males and 51 were females. The average age was (29±22) months. The mean duration of hospitalization and enteral nutrition were (11±7)d and (27±20)d respectively. Vomiting was the most common clinical presentation (72 cases, 56.3%). In 79 cases the problems were caused by mechanical injury, among which coins were most commonly seen. The rest 49 cases were caused by chemical injury. However, the duration of hospitalization ((13±8) d vs. (10±6)d, t=-3.089, P=0.002) and enteral nutrition ((39±22) vs. (19±14) d, t=-5.365, P=0.000) were longer in children with chemical injury than those with mechanical injury. A total of 112 cases got complete blood count and C-reactive protein both before and after enteral nutrition. Inflammatory markers, including leukocytes ((7.7±2.7) ×10(9)/L vs. (13.7±5.0) ×10(9)/L, t=12.244, P <0.05), neutrophils ((3.4±1.9)×10(9)/L vs. (9.4±4.6) ×10(9)/L, t=13.655, P<0.05), and C-reactive proteins (5.0(3.0,7.8) vs. 13.5(6.0,40.5) mg/L, Z=7.776, P <0.05) were significantly decreased. The nutritional markers, including the weight-for-age z score (-0.1 ± 1.0 vs. 0.0 ± 1.0, t=-2.622, P=0.010) and the prealbumin (0.1 ± 0.1 vs. 0.2 ± 0.0 g/L, t=-3.671, P=0.001) were significantly increased. Fifty-five (82.1%) children in mechanical injury group recovered in 4 weeks, while 27 (79.4%) children in chemical injury group recovered in 7 weeks. Conclusion: Enteral nutrition can provide adequate nutritional requirements for children with upper gastrointestinal injury, and may help to decrease imflammation and improve mucosal healing
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|a Journal Article
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|a Child
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|a Enteral nutrition
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|a Foreign bodies
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|a Gastrointestinal tract
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|a C-Reactive Protein
|2 NLM
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|a 9007-41-4
|2 NLM
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| 700 |
1 |
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|a Lou, J G
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Yu, J D
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Zhao, H
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Peng, K R
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Jiang, L Q
|e verfasserin
|4 aut
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|a Ma, M
|e verfasserin
|4 aut
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|a Chen, X F
|e verfasserin
|4 aut
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|a Chen, J
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Zhonghua er ke za zhi = Chinese journal of pediatrics
|d 1960
|g 56(2018), 11 vom: 02. Nov., Seite 861-865
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|g year:2018
|g number:11
|g day:02
|g month:11
|g pages:861-865
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