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231225s2019 xx |||||o 00| ||eng c |
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7 |
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|a 10.1111/jfd.12905
|2 doi
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|a pubmed24n0964.xml
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|e rakwb
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| 041 |
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|a eng
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| 100 |
1 |
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|a Ellul, Rebecca Marie
|e verfasserin
|4 aut
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| 245 |
1 |
0 |
|a Pathogenicity of Pasteurella sp. in lumpsuckers (Cyclopterus lumpus L.)
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| 264 |
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1 |
|c 2019
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| 336 |
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|a Text
|b txt
|2 rdacontent
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| 337 |
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|a ƒaComputermedien
|b c
|2 rdamedia
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| 338 |
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|a ƒa Online-Ressource
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|2 rdacarrier
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| 500 |
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|a Date Completed 14.01.2019
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|a Date Revised 30.09.2020
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a © 2018 John Wiley & Sons Ltd.
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|a The incidence of disease caused by Pasteurella sp. in farmed lumpsuckers in Norway has been steadily increasing in recent years, causing significant economic losses and fish welfare issues. The disease affects all life stages, both in hatcheries and after release into salmon cages. Therefore, it is important to establish robust challenge models, to be used for vaccine development. Exposure experiments via intramuscular and intraperitoneal injection underlined the high virulence of the bacteria, whereas the cohabitation and bath models allowed the chronic symptoms of the disease to be studied more accurately. Skin lesions and haemorrhage at the base of fins were observed in the more acute cases of the disease. Symptoms including white spots over the skin, especially around the eyes, characterized the chronic cases. The latter were most prominent from the bath challenge model. Histopathology indicated a systemic pattern of disease, whereas qPCR analysis from head kidney showed that bacteria may be present in survivor fish at the end of the challenges. In all the challenge models investigated, Pasteurella sp. was re-isolated from the fish, thus fulfilling Koch's postulates. These findings highlight the importance of screening of lumpsuckers prior to transfer to minimize the risks of carrying over asymptomatic carriers
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|a Journal Article
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|a challenge
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|a cleaner fish
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|a infection
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| 650 |
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|a lumpfish
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|a pasteurellosis
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| 650 |
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|a pathology
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| 650 |
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|a RNA, Ribosomal, 16S
|2 NLM
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| 700 |
1 |
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|a Walde, Cecilie
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Haugland, Gyri Teien
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Wergeland, Heidrun
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Rønneseth, Anita
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Journal of fish diseases
|d 1998
|g 42(2019), 1 vom: 01. Jan., Seite 35-46
|w (DE-627)NLM098166034
|x 1365-2761
|7 nnns
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| 773 |
1 |
8 |
|g volume:42
|g year:2019
|g number:1
|g day:01
|g month:01
|g pages:35-46
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| 856 |
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|u http://dx.doi.org/10.1111/jfd.12905
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