Proximity ligation assay to study protein-protein interactions of proteins on two different cells

Protein-protein interactions (PPI) by homo-, hetero- or oligo-merization in the cellular environment regulate cellular processes. PPI can be inhibited by antibodies, small molecules or peptides, and this inhibition has therapeutic value. A recently developed method, the proximity ligation assay (PLA...

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Veröffentlicht in:BioTechniques. - 1991. - 65(2018), 3 vom: 18. Sept., Seite 149-157
1. Verfasser: Sable, Rushikesh (VerfasserIn)
Weitere Verfasser: Jambunathan, Nithya, Singh, Sitanshu, Pallerla, Sandeep, Kousoulas, Konstantin G, Jois, Seetharama
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2018
Zugriff auf das übergeordnete Werk:BioTechniques
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't assays bioanalysis flourescence CD2 Antigens CD58 Antigens Histocompatibility Antigens Class II Membrane Proteins Proteins