Proximity ligation assay to study protein-protein interactions of proteins on two different cells

Protein-protein interactions (PPI) by homo-, hetero- or oligo-merization in the cellular environment regulate cellular processes. PPI can be inhibited by antibodies, small molecules or peptides, and this inhibition has therapeutic value. A recently developed method, the proximity ligation assay (PLA...

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Détails bibliographiques
Publié dans:BioTechniques. - 1991. - 65(2018), 3 vom: 18. Sept., Seite 149-157
Auteur principal: Sable, Rushikesh (Auteur)
Autres auteurs: Jambunathan, Nithya, Singh, Sitanshu, Pallerla, Sandeep, Kousoulas, Konstantin G, Jois, Seetharama
Format: Article en ligne
Langue:English
Publié: 2018
Accès à la collection:BioTechniques
Sujets:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't assays bioanalysis flourescence CD2 Antigens CD58 Antigens Histocompatibility Antigens Class II Membrane Proteins Proteins