Immunogenicity to cerliponase alfa intracerebroventricular enzyme replacement therapy for CLN2 disease : Results from a Phase 1/2 study

Copyright © 2018 Elsevier Inc. All rights reserved.

Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 197(2018) vom: 30. Dez., Seite 68-76
1. Verfasser: Cherukuri, Anu (VerfasserIn)
Weitere Verfasser: Cahan, Heather, de Hart, Greg, Van Tuyl, Andrea, Slasor, Peter, Bray, Laurie, Henshaw, Joshua, Ajayi, Temitayo, Jacoby, Dave, O'Neill, Charles A, Schweighardt, Becky
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2018
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Clinical Trial, Phase I Clinical Trial, Phase II Journal Article Research Support, Non-U.S. Gov't Anti-drug antibodies CLN2 Cerliponase alfa Enzyme replacement therapy Hypersensitivity Immunogenicity mehr... Neuronal ceroid lipofuscinosis Antibodies Antibodies, Neutralizing Recombinant Proteins Tripeptidyl-Peptidase 1 Immunoglobulin E 37341-29-0 Dipeptidyl-Peptidases and Tripeptidyl-Peptidases EC 3.4.14.- cerliponase alfa TPP1 protein, human EC 3.4.14.9