Antidepressant Effects of Probucol on Early-Symptomatic YAC128 Transgenic Mice for Huntington's Disease

Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder caused by a trinucleotide expansion in the HD gene, resulting in an extended polyglutamine tract in the protein huntingtin. HD is traditionally viewed as a movement disorder, but cognitive and neuropsychiatric symptom...

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Publié dans:Neural plasticity. - 1998. - 2018(2018) vom: 10., Seite 4056383
Auteur principal: de Paula Nascimento-Castro, Cristine (Auteur)
Autres auteurs: Wink, Ana Claudia, da Fônseca, Victor Silva, Bianco, Claudia Daniele, Winkelmann-Duarte, Elisa C, Farina, Marcelo, Rodrigues, Ana Lúcia S, Gil-Mohapel, Joana, de Bem, Andreza Fabro, Brocardo, Patricia S
Format: Article en ligne
Langue:English
Publié: 2018
Accès à la collection:Neural plasticity
Sujets:Journal Article Research Support, Non-U.S. Gov't Antidepressive Agents Antioxidants Dcx protein, mouse Doublecortin Protein Cholesterol 97C5T2UQ7J Probucol P3CTH044XJ