Multistep Interactions between Ibuprofen and Lipid Membranes

Ibuprofen (IBU) interacts with phosphatidylcholine membranes in three distinct steps as a function of concentration. In a first step (<10 μM), IBU electrostatically adsorbs to the lipid headgroups and gradually decreases the interfacial potential. This first step helps to facilitate the second st...

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Bibliographische Detailangaben

Veröffentlicht in:	Langmuir : the ACS journal of surfaces and colloids. - 1992. - 34(2018), 36 vom: 11. Sept., Seite 10782-10792
1. Verfasser:	Sun, Simou (VerfasserIn)
Weitere Verfasser:	Sendecki, Anne M, Pullanchery, Saranya, Huang, Da, Yang, Tinglu, Cremer, Paul S
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2018
Zugriff auf das übergeordnete Werk:	Langmuir : the ACS journal of surfaces and colloids
Schlagworte:	Journal Article Research Support, U.S. Gov't, Non-P.H.S. Fatty Acids, Monounsaturated Fluorescent Dyes Lipid Bilayers Phosphatidylethanolamines Phosphatidylglycerols Quaternary Ammonium Compounds Rhodamines lissamine rhodamine B mehr... 2609-88-3 1-palmitoyl-2-oleoylglycero-3-phosphoglycerol 81490-05-3 Cholesterol 97C5T2UQ7J 1,2-dioleoyloxy-3-(trimethylammonium)propane MR86K0XRQP 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine VM33LRU3A6 Ibuprofen WK2XYI10QM