Self-Assembled Curcumin-Poly(carboxybetaine methacrylate) Conjugates : Potent Nano-Inhibitors against Amyloid β-Protein Fibrillogenesis and Cytotoxicity

Fibrillogenesis of amyloid β-protein (Aβ) is a pathological hallmark of Alzheimer's disease, so inhibition of Aβ aggregation is considered as an important strategy for the precaution and treatment of AD. Curcumin (Cur) has been recognized as an effective inhibitor of Aβ fibrillogenesis, but its...

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Bibliographische Detailangaben
Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 35(2019), 5 vom: 05. Feb., Seite 1846-1857
1. Verfasser: Zhao, Guangfu (VerfasserIn)
Weitere Verfasser: Dong, Xiaoyan, Sun, Yan
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2019
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Amyloid beta-Peptides Methacrylates Peptide Fragments Polymethacrylic Acids amyloid beta-protein (1-42) polycarboxybetaine methacrylate Betaine 3SCV180C9W mehr... Curcumin IT942ZTH98