Distinct branches of the N-end rule pathway modulate the plant immune response

Bibliographische Detailangaben
Veröffentlicht in:	The New phytologist. - 1979. - 221(2019), 2 vom: 30. Jan., Seite 988-1000
1. Verfasser:	Vicente, Jorge (VerfasserIn)
Weitere Verfasser:	Mendiondo, Guillermina M, Pauwels, Jarne, Pastor, Victoria, Izquierdo, Yovanny, Naumann, Christin, Movahedi, Mahsa, Rooney, Daniel, Gibbs, Daniel J, Smart, Katherine, Bachmair, Andreas, Gray, Julie E, Dissmeyer, Nico, Castresana, Carmen, Ray, Rumiana V, Gevaert, Kris, Holdsworth, Michael J
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2019
Zugriff auf das übergeordnete Werk:	The New phytologist
Schlagworte:	Journal Article Research Support, Non-U.S. Gov't Group VII Ethylene Response Factor transcription factor N-end rule pathway amino-terminal glutamine amidase plant immunity proteostasis Arabidopsis Proteins Ethylenes Plant Growth Regulators mehr... ethylene 91GW059KN7 PRT6 protein, Arabidopsis EC 2.3.2.27 Ubiquitin-Protein Ligases

Beschreibung
Zusammenfassung:	© 2018 The Authors. New Phytologist © 2018 New Phytologist Trust. The N-end rule pathway is a highly conserved constituent of the ubiquitin proteasome system, yet little is known about its biological roles. Here we explored the role of the N-end rule pathway in the plant immune response. We investigated the genetic influences of components of the pathway and known protein substrates on physiological, biochemical and metabolic responses to pathogen infection. We show that the glutamine (Gln) deamidation and cysteine (Cys) oxidation branches are both components of the plant immune system, through the E3 ligase PROTEOLYSIS (PRT)6. In Arabidopsis thaliana Gln-specific amino-terminal (Nt)-amidase (NTAQ1) controls the expression of specific defence-response genes, activates the synthesis pathway for the phytoalexin camalexin and influences basal resistance to the hemibiotroph pathogen Pseudomonas syringae pv tomato (Pst). The Nt-Cys ETHYLENE RESPONSE FACTOR VII transcription factor substrates enhance pathogen-induced stomatal closure. Transgenic barley with reduced HvPRT6 expression showed enhanced resistance to Ps. japonica and Blumeria graminis f. sp. hordei, indicating a conserved role of the pathway. We propose that that separate branches of the N-end rule pathway act as distinct components of the plant immune response in flowering plants
Beschreibung:	Date Completed 18.02.2020 Date Revised 30.09.2020 published: Print-Electronic Citation Status MEDLINE
ISSN:	1469-8137
DOI:	10.1111/nph.15387