Assay for galactose-deficient IgA1 enables mechanistic studies with primary cells from IgA nephropathy patients
AIMS: IgA nephropathy, the most common primary glomerulonephritis worldwide, is characterized by glomerular deposition of galactose-deficient IgA1 and elevated serum levels of this IgA1 glycoform. Current ELISA methods lack sensitivity to assess galactose deficiency using small amounts of IgA1, whic...
Ausführliche Beschreibung
Bibliographische Detailangaben
| Veröffentlicht in: | BioTechniques. - 1993. - 65(2018), 2 vom: 01. Aug., Seite 71-77
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| 1. Verfasser: |
Reily, Colin
(VerfasserIn) |
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| Weitere Verfasser: |
Rizk, Dana V,
Julian, Bruce A,
Novak, Jan |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2018
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| Zugriff auf das übergeordnete Werk: | BioTechniques
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| Schlagworte: | Journal Article
Research Support, Non-U.S. Gov't
Research Support, N.I.H., Extramural
ELISA
IgA nephropathy
autoimmunity
chemiluminescence
colorimetric assay
galactose-deficient IgA1
glycosylation
mehr...
lectin
Acridines
Helix lectin
Immunoglobulin A
Lectins
Succinimides
4-(2-succinimidyloxycarbonylethyl)phenyl-10-methylacridinium-9-carboxylate
87198-89-8
Galactose
X2RN3Q8DNE |
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