|
|
|
|
| LEADER |
01000caa a22002652 4500 |
| 001 |
NLM287177696 |
| 003 |
DE-627 |
| 005 |
20250223221036.0 |
| 007 |
cr uuu---uuuuu |
| 008 |
231225s2018 xx |||||o 00| ||chi c |
| 024 |
7 |
|
|a 10.3760/cma.j.issn.0578-1310.2018.08.005
|2 doi
|
| 028 |
5 |
2 |
|a pubmed25n0957.xml
|
| 035 |
|
|
|a (DE-627)NLM287177696
|
| 035 |
|
|
|a (NLM)30078238
|
| 040 |
|
|
|a DE-627
|b ger
|c DE-627
|e rakwb
|
| 041 |
|
|
|a chi
|
| 100 |
1 |
|
|a Fang, C
|e verfasserin
|4 aut
|
| 245 |
1 |
0 |
|a Clinical characteristics and antimicrobial resistance of pneumococcal infections from 9 children's hospitals in 2016
|
| 264 |
|
1 |
|c 2018
|
| 336 |
|
|
|a Text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a ƒaComputermedien
|b c
|2 rdamedia
|
| 338 |
|
|
|a ƒa Online-Ressource
|b cr
|2 rdacarrier
|
| 500 |
|
|
|a Date Completed 01.04.2019
|
| 500 |
|
|
|a Date Revised 01.04.2019
|
| 500 |
|
|
|a published: Print
|
| 500 |
|
|
|a Citation Status MEDLINE
|
| 520 |
|
|
|a Objective: To describe the clinical characteristics of pneumococcal infections and drug resistance of Streptococcus pneumoniae isolates from children's hospitals, which would provide reference for preventing and treating pneumococcal diseases. Methods: This was a prevalence survey. In this study, the age, specimen type, monthly distribution characteristics, and antimicrobial resistance of Streptococcus pneumoniae isolates from 9 children's hospitals in China were investigated between January 1, 2016 and December 31, 2016. The WHONET 5.6 software was used to analyze the antibiotic susceptibility of Streptococcus pneumoniae. The comparison of rates was performed by Chi-square test. Results: A total of 6 200 isolates of streptococcus pneumoniae were obtained, namely, 95.1% (5 876/6 177) from the respiratory tract specimens, 2.2% (136/6 177) from blood specimens and 0.4% (24/6 177) from cerebrospinal fluid specimens. The isolates were mainly from children older than 1 and younger than 5 years (54.7%, 3 381/6 185) . Most of strains (33.2%, 1 184/3 563) were isolated in November, December and January. Streptococcus pneumoniae isolates were completely sensitive to vancomycin (100.0%, 6 189/6 189) , linezolid (100.0%, 6 030/6 030) , moxifloxacin (100.0%, 3 064/3 064) , highly sensitive to levofloxacin (99.8%, 5 528/5 540), ertapenem (98.8%, 3 024/3 061) and lowly sensitive to erythromycin (1.7%, 102/6 016), clindamycin (3.7%, 116/3 136), and tetracycline (5%, 244/4 877), respectively. According to the parenteral susceptibility breakpoints for non-meningitis isolates, the sensitivity of Streptocococus pneumoniae to penicillin from children's hospital of Chongqing Medical University (49.3%, 892/1 809) was significantly lower than those of other hospitals (χ(2)=1 268.161, P<0.05) . Conclusions:Streptococcus pneumoniae is mainly isolated from respiratory tract, from children older than 1 and younger than 5 years and during November to January in tertiary children's hospital of China. The Streptococcus pneumoniae from children is highly sensitive to vancomycin, linezolid, moxifloxacin, levofloxacin. There are also significant differences in the sensitivity of penicillin for Streptococcus pneumoniae from different hospitals
|
| 650 |
|
4 |
|a Journal Article
|
| 650 |
|
4 |
|a Child
|
| 650 |
|
4 |
|a Drug susceptibility testing
|
| 650 |
|
4 |
|a Pneumococcal infections
|
| 650 |
|
7 |
|a Anti-Bacterial Agents
|2 NLM
|
| 700 |
1 |
|
|a Chen, X J
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Zhou, M M
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Chen, Y H
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Zhao, R Z
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Deng, J K
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Jing, C M
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Xu, H M
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Yang, J H
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Chen, Y P
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Zhang, H
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Zhang, T
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Cao, S C
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Deng, H L
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Wang, C Q
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Wang, A M
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Yu, H
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Wang, S F
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Lin, A W
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Wang, X
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Cao, Q
|e verfasserin
|4 aut
|
| 773 |
0 |
8 |
|i Enthalten in
|t Zhonghua er ke za zhi = Chinese journal of pediatrics
|d 1960
|g 56(2018), 8 vom: 02. Aug., Seite 582-586
|w (DE-627)NLM136249191
|x 0578-1310
|7 nnns
|
| 773 |
1 |
8 |
|g volume:56
|g year:2018
|g number:8
|g day:02
|g month:08
|g pages:582-586
|
| 856 |
4 |
0 |
|u http://dx.doi.org/10.3760/cma.j.issn.0578-1310.2018.08.005
|3 Volltext
|
| 912 |
|
|
|a GBV_USEFLAG_A
|
| 912 |
|
|
|a SYSFLAG_A
|
| 912 |
|
|
|a GBV_NLM
|
| 912 |
|
|
|a GBV_ILN_11
|
| 912 |
|
|
|a GBV_ILN_20
|
| 912 |
|
|
|a GBV_ILN_22
|
| 912 |
|
|
|a GBV_ILN_24
|
| 912 |
|
|
|a GBV_ILN_31
|
| 912 |
|
|
|a GBV_ILN_39
|
| 912 |
|
|
|a GBV_ILN_40
|
| 912 |
|
|
|a GBV_ILN_50
|
| 912 |
|
|
|a GBV_ILN_61
|
| 912 |
|
|
|a GBV_ILN_65
|
| 912 |
|
|
|a GBV_ILN_69
|
| 912 |
|
|
|a GBV_ILN_70
|
| 912 |
|
|
|a GBV_ILN_72
|
| 912 |
|
|
|a GBV_ILN_120
|
| 912 |
|
|
|a GBV_ILN_130
|
| 912 |
|
|
|a GBV_ILN_227
|
| 912 |
|
|
|a GBV_ILN_244
|
| 912 |
|
|
|a GBV_ILN_285
|
| 912 |
|
|
|a GBV_ILN_294
|
| 912 |
|
|
|a GBV_ILN_350
|
| 912 |
|
|
|a GBV_ILN_665
|
| 912 |
|
|
|a GBV_ILN_813
|
| 951 |
|
|
|a AR
|
| 952 |
|
|
|d 56
|j 2018
|e 8
|b 02
|c 08
|h 582-586
|