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231225s2018 xx |||||o 00| ||eng c |
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|a 10.5713/ajas.18.0173
|2 doi
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|a pubmed24n0956.xml
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|a (DE-627)NLM286965992
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|a (NLM)30056669
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|a DE-627
|b ger
|c DE-627
|e rakwb
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| 041 |
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|a eng
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| 100 |
1 |
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|a Jin, Sihua
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Association of polymorphisms in Pit-1 gene with growth and feed efficiency in meat-type chickens
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|c 2018
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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| 338 |
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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|a Date Revised 01.10.2020
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|a published: Print-Electronic
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|a Citation Status PubMed-not-MEDLINE
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|a OBJECTIVE: The pituitary specific transcription factor-1 (Pit-1) gene is responsible for pituitary development and growth hormone expression and is regarded as a pivotal candidate gene for growth and production in chickens. Therefore, the aim of this study was to investigate the association of Pit-1 polymorphisms with growth and feed efficiency traits in yellow meat-type chickens
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|a METHODS: In the present study, five single nucleotide polymorphisms (SNPs) of Pit-1 were selected and genotyped by high-throughput matrix-assisted laser desorption-ionization time-of-flight mass spectrometry in 724 meat-type chickens
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| 520 |
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|a RESULTS: Association analysis showed that rs13687126 of Pit-1 was strongly associated with body weight gain (BWG) and feed intake (FI) (p<0.05), and that rs13687128 was significantly correlated with body weight at 70 days of age (BW70), BWG and feed conversion ratio (FCR) (p<0.05). SNP rs13905622 was strongly related to BW70 and FCR (p<0.05). Furthermore, birds with the GG genotype of rs13687126 had larger BWG and FI than those with the AG genotype (p<0.05). Individuals with the TT genotype of rs13687128 were significantly higher BW70 and BWG than those of the CT and CC genotype, while FCR was just the opposite (p<0.05). For rs13905622, the AA chickens showed strongly larger BW70 and lower FCR compared with the AT and TT chickens (p<0.05). Additionally, an ACA haplotype based on rs13687126, rs13687128, and rs13905622 had significant effects on BW70 and FCR (p<0.05)
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|a CONCLUSION: Our studies thus provide crucial evidence for the relationship between polymorphisms of Pit-1 and growth and feed efficiency traits which may be useful for meat-type chicken breeding programs
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|a Journal Article
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|a Association
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|a Chicken
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|a Feed Conversion Ratio
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| 650 |
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4 |
|a Pit-1
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| 650 |
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|a Single Nucleotide Polymorphism
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| 700 |
1 |
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|a He, Tingting
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Yang, Lei
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Tong, Yucui
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Chen, Xingyong
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Geng, Zhaoyu
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Asian-Australasian journal of animal sciences
|d 1998
|g 31(2018), 11 vom: 28. Nov., Seite 1685-1690
|w (DE-627)NLM098195883
|x 1011-2367
|7 nnns
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| 773 |
1 |
8 |
|g volume:31
|g year:2018
|g number:11
|g day:28
|g month:11
|g pages:1685-1690
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| 856 |
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|u http://dx.doi.org/10.5713/ajas.18.0173
|3 Volltext
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