Amyloid-β Peptide Triggers Membrane Remodeling in Supported Lipid Bilayers Depending on Their Hydrophobic Thickness

Amyloid-β (Aβ) peptide has been implicated in Alzheimer's disease, which is a leading cause of death worldwide. The interaction of Aβ peptides with the lipid bilayers of neuronal cells is a critical step in disease pathogenesis. Recent evidence indicates that lipid bilayer thickness influences...

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Publié dans:	Langmuir : the ACS journal of surfaces and colloids. - 1985. - 34(2018), 32 vom: 14. Aug., Seite 9548-9560
Auteur principal:	Meker, Sigalit (Auteur)
Autres auteurs:	Chin, Hokyun, Sut, Tun Naw, Cho, Nam-Joon
Format:	Article en ligne
Langue:	English
Publié:	2018
Accès à la collection:	Langmuir : the ACS journal of surfaces and colloids
Sujets:	Journal Article Research Support, Non-U.S. Gov't Amyloid beta-Peptides Lipid Bilayers Peptide Fragments Phosphatidylcholines amyloid beta-protein (1-40) 1,2-dilauroylphosphatidylcholine 18285-71-7 1,2-oleoylphosphatidylcholine plus... EDS2L3ODLV 1-palmitoyl-2-oleoylphosphatidylcholine TE895536Y5