Luciferase complementation based-detection of G-protein-coupled receptor activity
Protein complementation assays (PCA) are used as pharmacological tools, enabling a wide array of applications, ranging from studies of protein-protein interactions to second messenger effects. Methods to detect activities of G protein-coupled receptors (GPCRs) have particular relevance for drug scre...
Ausführliche Beschreibung
Bibliographische Detailangaben
Veröffentlicht in: | BioTechniques. - 1993. - 65(2018), 1 vom: 01. Juli, Seite 9-14
|
1. Verfasser: |
Yano, Hideaki
(VerfasserIn) |
Weitere Verfasser: |
Cai, Ning Sheng,
Javitch, Jonathan A,
Ferré, Sergi |
Format: | Online-Aufsatz
|
Sprache: | English |
Veröffentlicht: |
2018
|
Zugriff auf das übergeordnete Werk: | BioTechniques
|
Schlagworte: | Journal Article
Research Support, N.I.H., Intramural
Research Support, Non-U.S. Gov't
GPCR
assay development
biosensor
complementation
dopamine receptor
luciferase
Receptors, G-Protein-Coupled
mehr...
Recombinant Fusion Proteins
Luciferases
EC 1.13.12.- |