|
|
|
|
| LEADER |
01000caa a22002652c 4500 |
| 001 |
NLM286514591 |
| 003 |
DE-627 |
| 005 |
20250223195259.0 |
| 007 |
cr uuu---uuuuu |
| 008 |
231225s2018 xx |||||o 00| ||eng c |
| 024 |
7 |
|
|a 10.1109/TUFFC.2018.2855181
|2 doi
|
| 028 |
5 |
2 |
|a pubmed25n0954.xml
|
| 035 |
|
|
|a (DE-627)NLM286514591
|
| 035 |
|
|
|a (NLM)30010555
|
| 040 |
|
|
|a DE-627
|b ger
|c DE-627
|e rakwb
|
| 041 |
|
|
|a eng
|
| 100 |
1 |
|
|a Liu, Hao-Li
|e verfasserin
|4 aut
|
| 245 |
1 |
0 |
|a Design and Implementation of a Transmit/Receive Ultrasound Phased Array for Brain Applications
|
| 264 |
|
1 |
|c 2018
|
| 336 |
|
|
|a Text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a ƒaComputermedien
|b c
|2 rdamedia
|
| 338 |
|
|
|a ƒa Online-Ressource
|b cr
|2 rdacarrier
|
| 500 |
|
|
|a Date Completed 17.09.2019
|
| 500 |
|
|
|a Date Revised 17.09.2019
|
| 500 |
|
|
|a published: Print-Electronic
|
| 500 |
|
|
|a Citation Status MEDLINE
|
| 520 |
|
|
|a Focused ultrasound phased array systems have attracted increased attention for brain therapy applications. However, such systems currently lack a direct and real-time method to intraoperatively monitor ultrasound pressure distribution for securing treatment. This study proposes a dual-mode ultrasound phased array system design to support transmit/receive operations for concurrent ultrasound exposure and backscattered focal beam reconstruction through a spherically focused ultrasound array. A 256-channel ultrasound transmission system was used to transmit focused ultrasonic energy (full 256 channels), with an extended implementation of multiple-channel receiving function (up to 64 channels) using the same 256-channel ultrasound array. A coherent backscatter-received beam formation algorithm was implemented to map the point spread function (PSF) and focal beam distribution under a free-field/transcranial environment setup, with the backscattering generated from a strong scatterer (a point reflector or a microbubble-perfused tube) or a weakly scattered tissue-mimicking graphite phantom. Our results showed that PSF and focal beam can be successfully reconstructed and visualized in free-field conditions and can also be transcranially reconstructed following skull-induced aberration correction. In vivo experiments were conducted to demonstrate its capability to preoperatively and semiquantitatively map a focal beam to guide blood-brain barrier opening. The proposed system may have potential for real-time guidance of ultrasound brain intervention, and may facilitate the design of a dual-mode ultrasound phased array for brain therapeutic applications
|
| 650 |
|
4 |
|a Journal Article
|
| 650 |
|
4 |
|a Research Support, Non-U.S. Gov't
|
| 700 |
1 |
|
|a Tsai, Chih-Hung
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Jan, Chen-Kai
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Chang, Hsin-Yu
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Huang, Sheng-Min
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Li, Meng-Lin
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Qiu, Weibao
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Zheng, Hairong
|e verfasserin
|4 aut
|
| 773 |
0 |
8 |
|i Enthalten in
|t IEEE transactions on ultrasonics, ferroelectrics, and frequency control
|d 1986
|g 65(2018), 10 vom: 16. Okt., Seite 1756-1767
|w (DE-627)NLM098181017
|x 1525-8955
|7 nnas
|
| 773 |
1 |
8 |
|g volume:65
|g year:2018
|g number:10
|g day:16
|g month:10
|g pages:1756-1767
|
| 856 |
4 |
0 |
|u http://dx.doi.org/10.1109/TUFFC.2018.2855181
|3 Volltext
|
| 912 |
|
|
|a GBV_USEFLAG_A
|
| 912 |
|
|
|a SYSFLAG_A
|
| 912 |
|
|
|a GBV_NLM
|
| 912 |
|
|
|a GBV_ILN_22
|
| 912 |
|
|
|a GBV_ILN_24
|
| 912 |
|
|
|a GBV_ILN_350
|
| 951 |
|
|
|a AR
|
| 952 |
|
|
|d 65
|j 2018
|e 10
|b 16
|c 10
|h 1756-1767
|