The Penetration Depth for Hanatoxin Partitioning into the Membrane Hydrocarbon Core Measured with Neutron Reflectivity

Hanatoxin (HaTx) from spider venom works as an inhibitor of Kv2.1 channels, most likely by interacting with the voltage sensor (VS). However, the way in which this water-soluble peptide modifies the gating remains poorly understood as the VS is deeply embedded within the bilayer, although it would c...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 34(2018), 30 vom: 31. Juli, Seite 9036-9046
1. Verfasser: Hsieh, Meng-Hsuan (VerfasserIn)
Weitere Verfasser: Huang, Po-Tsang, Liou, Horng-Huei, Liang, Po-Huang, Chen, Pei-Ming, Holt, Stephen A, Yu, Isaac Furay, James, Michael, Shiau, Yu-Shuan, Lee, Ming-Tao, Lin, Tsang-Lang, Lou, Kuo-Long
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2018
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't