Role of Lipid Coating in the Transport of Nanodroplets across the Pulmonary Surfactant Layer Revealed by Molecular Dynamics Simulations
Hydrophilic drugs can be delivered into lungs via nebulization for both local and systemic therapies. Once inhaled, ultrafine nanodroplets preferentially deposit in the alveolar region, where they first interact with the pulmonary surfactant (PS) layer, with nature of the interaction determining bot...
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Bibliographische Detailangaben
| Veröffentlicht in: | Langmuir : the ACS journal of surfaces and colloids. - 1992. - 34(2018), 30 vom: 31. Juli, Seite 9054-9063
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| 1. Verfasser: |
Xu, Yan
(VerfasserIn) |
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| Weitere Verfasser: |
Li, Shixin,
Luo, Zhen,
Ren, Hao,
Zhang, Xianren,
Huang, Fang,
Zuo, Yi Y,
Yue, Tongtao |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2018
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| Zugriff auf das übergeordnete Werk: | Langmuir : the ACS journal of surfaces and colloids
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| Schlagworte: | Journal Article
Research Support, Non-U.S. Gov't
Lipids
Pulmonary Surfactants |
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