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231225s2018 xx |||||o 00| ||eng c |
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|a 10.1016/j.jsha.2017.11.001
|2 doi
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|a pubmed24n0954.xml
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|a (NLM)29983492
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|a DE-627
|b ger
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|e rakwb
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|a eng
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|a Smettei, Osama A
|e verfasserin
|4 aut
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|a Ultra-fast, low dose high-pitch (FLASH) versus prospectively-gated coronary computed tomography angiography
|b Comparison of image quality and patient radiation exposure
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|c 2018
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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|a Date Revised 18.03.2022
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|a published: Print-Electronic
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|a Citation Status PubMed-not-MEDLINE
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|a BACKGROUND: Coronary computed tomography angiography (CCTA) is increasingly being used for the evaluation of coronary artery disease; however, radiation exposure remains a major limitation of its use
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|a OBJECTIVE: To compare image quality and radiation exposure in two groups of patients undergoing CCTA using a 256-slice dual-source helical computed tomography scanner with high-pitch (FLASH) or prospective [step-and-shoot (SAS)] gating protocols
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|a METHODS: A prospective, single-center study was performed in our cardiac center. In total, 162 patients underwent CCTA with either FLASH or SAS scanning protocols. Subjective image quality was graded on the basis of a four-point grading system (1, non-diagnostic; 2, adequate; 3, good; 4, excellent). Objective image quality was assessed using image signal, noise, and signal-to-noise ratio (SNR). The effective radiation dose was also estimated
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|a RESULTS: The clinical and demographic characteristics of the patients in both groups were similar. The median age of the patients in both groups was 48.43 years, and males accounted for 63% and 68.7% of the FLASH and SAS groups, respectively. We found that the subjective image quality obtained with the FLASH protocol was superior to that obtained with the SAS protocol (3.35 ± 0.6 mSv vs. 2.82 ± 0.61 mSv; p < 0.001). Image noise was higher in the FLASH group but was not statistically significant (25.0 ± 6.13 vs. 24.0 ± 6.8; p = 0.10), whereas the signal and SNR was significantly higher with the FLASH protocol than with the SAS protocol [(469 ± 116 vs. 397 ± 106; p > 0.001) and (21.6 ± 8.7 mSv vs. 16.6 ± 7.7 mSv; p < 0.001), respectively]. Radiation exposure was 62% lower in the FLASH protocol than in the SAS protocol, (1.9 ± 0.4 mSv vs. 5.12 ± 1.8 mSv; p < 0.001)
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|a CONCLUSION: The use of 256-slice CCTA performed with the FLASH protocol has a better objective and subjective image quality as well as lower radiation exposure when compared with the use of prospective electrocardiography gating
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|a Journal Article
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|a Cardiac CT protocol
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|a Computed tomography angiography
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|a ECG gating
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|a Radiation exposure
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|a Sayed, Sawsan
|e verfasserin
|4 aut
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|a M Al Habib, Abdullah
|e verfasserin
|4 aut
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|a Alharbi, Fahad
|e verfasserin
|4 aut
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|a Abazid, Rami M
|e verfasserin
|4 aut
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|i Enthalten in
|t Journal of the Saudi Heart Association
|d 1999
|g 30(2018), 3 vom: 14. Juli, Seite 165-171
|w (DE-627)NLM098225227
|x 1016-7315
|7 nnns
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|g volume:30
|g year:2018
|g number:3
|g day:14
|g month:07
|g pages:165-171
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|u http://dx.doi.org/10.1016/j.jsha.2017.11.001
|3 Volltext
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|h 165-171
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