Heterozygous CDKL5 Knockout Female Mice Are a Valuable Animal Model for CDKL5 Disorder
CDKL5 disorder is a severe neurodevelopmental disorder caused by mutations in the X-linked CDKL5 (cyclin-dependent kinase-like five) gene. CDKL5 disorder primarily affects girls and is characterized by early-onset epileptic seizures, gross motor impairment, intellectual disability, and autistic feat...
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Bibliographische Detailangaben
| Veröffentlicht in: | Neural plasticity. - 1998. - 2018(2018) vom: 01., Seite 9726950
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| 1. Verfasser: |
Fuchs, Claudia
(VerfasserIn) |
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| Weitere Verfasser: |
Gennaccaro, Laura,
Trazzi, Stefania,
Bastianini, Stefano,
Bettini, Simone,
Lo Martire, Viviana,
Ren, Elisa,
Medici, Giorgio,
Zoccoli, Giovanna,
Rimondini, Roberto,
Ciani, Elisabetta |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2018
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| Zugriff auf das übergeordnete Werk: | Neural plasticity
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| Schlagworte: | Journal Article
Research Support, Non-U.S. Gov't
Protein Serine-Threonine Kinases
EC 2.7.11.1
CDKL5 protein, mouse
EC 2.7.11.22 |
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