|
|
|
|
| LEADER |
01000naa a22002652 4500 |
| 001 |
NLM285885693 |
| 003 |
DE-627 |
| 005 |
20231225050430.0 |
| 007 |
cr uuu---uuuuu |
| 008 |
231225s2018 xx |||||o 00| ||eng c |
| 024 |
7 |
|
|a 10.1093/jxb/ery242
|2 doi
|
| 028 |
5 |
2 |
|a pubmed24n0952.xml
|
| 035 |
|
|
|a (DE-627)NLM285885693
|
| 035 |
|
|
|a (NLM)29945243
|
| 040 |
|
|
|a DE-627
|b ger
|c DE-627
|e rakwb
|
| 041 |
|
|
|a eng
|
| 100 |
1 |
|
|a Emiliani, Julia
|e verfasserin
|4 aut
|
| 245 |
1 |
2 |
|a A role for β,β-xanthophylls in Arabidopsis UV-B photoprotection
|
| 264 |
|
1 |
|c 2018
|
| 336 |
|
|
|a Text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a ƒaComputermedien
|b c
|2 rdamedia
|
| 338 |
|
|
|a ƒa Online-Ressource
|b cr
|2 rdacarrier
|
| 500 |
|
|
|a Date Completed 15.10.2019
|
| 500 |
|
|
|a Date Revised 15.10.2019
|
| 500 |
|
|
|a published: Print
|
| 500 |
|
|
|a Citation Status MEDLINE
|
| 520 |
|
|
|a Plastidial isoprenoids, such as carotenoids and tocopherols, are important anti-oxidant metabolites synthesized in plastids from precursors generated by the methylerythritol 4-phosphate (MEP) pathway. In this study, we found that irradiation of Arabidopsis thaliana plants with UV-B caused a strong increase in the accumulation of the photoprotective xanthophyll zeaxanthin but also resulted in slightly higher levels of γ-tocopherol. Plants deficient in the MEP enzymes 1-deoxy-D-xylulose 5-phosphate synthase and 1-hydroxy-2-methyl-2-butenyl 4-diphosphate synthase showed a general reduction in both carotenoids and tocopherols and this was associated with increased DNA damage and decreased photosynthesis after exposure to UV-B. Genetic blockage of tocopherol biosynthesis did not affect DNA damage accumulation. In contrast, lut2 mutants that accumulate β,β-xanthophylls showed decreased DNA damage when irradiated with UV-B. Analysis of aba2 mutants showed that UV-B protection was not mediated by ABA (a hormone derived from β,β-xanthophylls). Plants accumulating β,β-xanthophylls also showed decreased oxidative damage and increased expression of DNA-repair enzymes, suggesting that this may be a mechanism for these plants to decrease DNA damage. In addition, in vitro experiments also provided evidence that β,β-xanthophylls can directly protect against DNA damage by absorbing radiation. Together, our results suggest that xanthophyll-cycle carotenoids that protect against excess illumination may also contribute to protection against UV-B
|
| 650 |
|
4 |
|a Journal Article
|
| 650 |
|
4 |
|a Research Support, Non-U.S. Gov't
|
| 650 |
|
7 |
|a 2-C-methylerythritol 4-phosphate
|2 NLM
|
| 650 |
|
7 |
|a Sugar Phosphates
|2 NLM
|
| 650 |
|
7 |
|a Xanthophylls
|2 NLM
|
| 650 |
|
7 |
|a Erythritol
|2 NLM
|
| 650 |
|
7 |
|a RA96B954X6
|2 NLM
|
| 700 |
1 |
|
|a D'Andrea, Lucio
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Lorena Falcone Ferreyra, María
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Maulión, Evangelina
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Rodriguez, Eduardo
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Rodriguez-Concepción, Manuel
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Casati, Paula
|e verfasserin
|4 aut
|
| 773 |
0 |
8 |
|i Enthalten in
|t Journal of experimental botany
|d 1985
|g 69(2018), 20 vom: 14. Sept., Seite 4921-4933
|w (DE-627)NLM098182706
|x 1460-2431
|7 nnns
|
| 773 |
1 |
8 |
|g volume:69
|g year:2018
|g number:20
|g day:14
|g month:09
|g pages:4921-4933
|
| 856 |
4 |
0 |
|u http://dx.doi.org/10.1093/jxb/ery242
|3 Volltext
|
| 912 |
|
|
|a GBV_USEFLAG_A
|
| 912 |
|
|
|a SYSFLAG_A
|
| 912 |
|
|
|a GBV_NLM
|
| 912 |
|
|
|a GBV_ILN_350
|
| 951 |
|
|
|a AR
|
| 952 |
|
|
|d 69
|j 2018
|e 20
|b 14
|c 09
|h 4921-4933
|