Development of Zwitterionic Polypeptide Nanoformulation with High Doxorubicin Loading Content for Targeted Drug Delivery

Much attention has been drawn to targeted nanodrug delivery systems due to their high therapeutic efficacy in cancer treatment. In this work, doxorubicin (DOX) was incorporated into a zwitterionic arginyl-glycyl-aspartic acid (RGD)-conjugated polypeptide by an emulsion solvent evaporation technique...

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Publié dans:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 35(2019), 5 vom: 05. Feb., Seite 1273-1283
Auteur principal: Lin, Weifeng (Auteur)
Autres auteurs: Ma, Guanglong, Yuan, Zhefan, Qian, Haofeng, Xu, Liangbo, Sidransky, Elie, Chen, Shengfu
Format: Article en ligne
Langue:English
Publié: 2019
Accès à la collection:Langmuir : the ACS journal of surfaces and colloids
Sujets:Journal Article Research Support, Non-U.S. Gov't Antineoplastic Agents Drug Carriers Peptides, Cyclic Polylysine 25104-18-1 Polyglutamic Acid 25513-46-6 poly(glutamic acid-lysine) plus... 27456-64-0 Doxorubicin 80168379AG