Development of Zwitterionic Polypeptide Nanoformulation with High Doxorubicin Loading Content for Targeted Drug Delivery

Much attention has been drawn to targeted nanodrug delivery systems due to their high therapeutic efficacy in cancer treatment. In this work, doxorubicin (DOX) was incorporated into a zwitterionic arginyl-glycyl-aspartic acid (RGD)-conjugated polypeptide by an emulsion solvent evaporation technique...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 35(2019), 5 vom: 05. Feb., Seite 1273-1283
1. Verfasser: Lin, Weifeng (VerfasserIn)
Weitere Verfasser: Ma, Guanglong, Yuan, Zhefan, Qian, Haofeng, Xu, Liangbo, Sidransky, Elie, Chen, Shengfu
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2019
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Antineoplastic Agents Drug Carriers Peptides, Cyclic Polylysine 25104-18-1 Polyglutamic Acid 25513-46-6 poly(glutamic acid-lysine) mehr... 27456-64-0 Doxorubicin 80168379AG