Gel Phase Membrane Retards Amyloid β-Peptide (1-42) Fibrillation by Restricting Slaved Diffusion of Peptides on Lipid Bilayers

Plasma membranes in the human brain can interact with amyloid β-peptide (1-42; Aβ42) and induce Aβ42 fibrillation, which is considered to be a crucial process underlying the neurotoxicity of Aβ42 and the pathogenesis of Alzheimer's disease (AD). However, the mechanism of membrane-mediated Aβ42...

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Publié dans:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 34(2018), 28 vom: 17. Juli, Seite 8408-8414
Auteur principal: Yang, Mengting (Auteur)
Autres auteurs: Wang, Kang, Lin, Jiake, Wang, Liqun, Wei, Feng, Zhu, Jintao, Zheng, Wanquan, Shen, Lei
Format: Article en ligne
Langue:English
Publié: 2018
Accès à la collection:Langmuir : the ACS journal of surfaces and colloids
Sujets:Journal Article Research Support, Non-U.S. Gov't Amyloid beta-Peptides Gels Lipid Bilayers