Bioinert Control of Zwitterionic Poly(ethylene terephtalate) Fibrous Membranes

Poly(ethylene terephtalate) (PET)-based materials face general biofouling issues that we addressed by grafting a copolymer of glycidyl methacrylate and sulfobetaine methacrylate, poly(GMA- r-SBMA). The grafting procedure involved a dip-coating step followed by UV-exposure and led to successful graft...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 35(2019), 5 vom: 05. Feb., Seite 1727-1739
1. Verfasser: Tang, Shuo-Hsi (VerfasserIn)
Weitere Verfasser: Domino, Maria Ysabel, Venault, Antoine, Lin, Hao-Tung, Hsieh, Chun, Higuchi, Akon, Chinnathambi, Arunachalam, Alharbi, Sulaiman Ali, Tayo, Lemmuel L, Chang, Yung
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2019
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Epoxy Compounds Methacrylates Polyethylene Terephthalates Betaine 3SCV180C9W sulfobetaine 8CVU22OCJW glycidyl methacrylate R8WN29J8VF
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520 |a Poly(ethylene terephtalate) (PET)-based materials face general biofouling issues that we addressed by grafting a copolymer of glycidyl methacrylate and sulfobetaine methacrylate, poly(GMA- r-SBMA). The grafting procedure involved a dip-coating step followed by UV-exposure and led to successful grafting of the copolymer as evidenced by X-ray photoelectron spectroscopy and zeta potential measurements. It did not modify the pore size nor the porosity of the PET membranes. In addition, their surface hydrophilicity was considerably improved, with a water contact angle falling to 30° in less than 20 s and 0° in less than 1 min. The effect of copolymer concentration in the coating bath (dip-coating procedure) and UV exposure time (UV step) were scrutinized during biofouling studies involving several bacteria such as Escherichia coli and Stenotrophomonas maltophilia, but also whole blood and HT1080 fibroblasts cells. The results indicate that if all conditions led to improved biofouling mitigation, due to the efficiency of the zwitterionic copolymer and grafting procedure, a higher concentration (15 mg/mL) and longer UV exposure time (at least 10 min) enhanced the grafting density which reflected on the biofouling results and permitted a better general biofouling control regardless of the nature of the biofoulant (bacteria, blood cells, fibroblasts) 
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650 4 |a Research Support, Non-U.S. Gov't 
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650 7 |a Methacrylates  |2 NLM 
650 7 |a Polyethylene Terephthalates  |2 NLM 
650 7 |a Betaine  |2 NLM 
650 7 |a 3SCV180C9W  |2 NLM 
650 7 |a sulfobetaine  |2 NLM 
650 7 |a 8CVU22OCJW  |2 NLM 
650 7 |a glycidyl methacrylate  |2 NLM 
650 7 |a R8WN29J8VF  |2 NLM 
700 1 |a Domino, Maria Ysabel  |e verfasserin  |4 aut 
700 1 |a Venault, Antoine  |e verfasserin  |4 aut 
700 1 |a Lin, Hao-Tung  |e verfasserin  |4 aut 
700 1 |a Hsieh, Chun  |e verfasserin  |4 aut 
700 1 |a Higuchi, Akon  |e verfasserin  |4 aut 
700 1 |a Chinnathambi, Arunachalam  |e verfasserin  |4 aut 
700 1 |a Alharbi, Sulaiman Ali  |e verfasserin  |4 aut 
700 1 |a Tayo, Lemmuel L  |e verfasserin  |4 aut 
700 1 |a Chang, Yung  |e verfasserin  |4 aut 
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