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231225s2018 xx |||||o 00| ||eng c |
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|a 10.1021/acs.langmuir.8b01445
|2 doi
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|a pubmed24n0948.xml
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|a (NLM)29809016
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|a DE-627
|b ger
|c DE-627
|e rakwb
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| 041 |
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|a eng
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| 100 |
1 |
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|a Zhao, Wenrong
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Self-Assembled Magnetic Viruslike Particles for Encapsulation and Delivery of Deoxyribonucleic Acid
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| 264 |
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|c 2018
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| 336 |
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
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|2 rdamedia
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|a ƒa Online-Ressource
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|2 rdacarrier
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|a Date Completed 14.03.2019
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|a Date Revised 14.03.2019
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a Developing nontoxic artificial carriers for stimuli-responsive capture, transport, and delivery of biomolecules is of immense scientific interest. Herein, for the first time, we synthesize a double-tailed cationic surfactant, (C16H33)2(CH3)2N+[FeCl3Br]-, which possesses magnetic properties [magnetic surfactants (Mag-Surfs)]. The time-dependent formation of virus-shaped hybrid mixed assemblies of polyoxometalates (POMs) {Mo72Fe30}/Mag-Surf with hollow-shell structures is followed. These structures serve well as robust high-surface-area shuttles, which can be manipulated with applied magnetic fields. By using cationic Mag-Surfs, the anionic POMs and DNA can be complexed in these ternary mixtures. These virus-shaped complexes act as nanoanchors and nanomotors, which can be utilized for binding, anchoring, and delivery of biomolecules, such as DNA. It is found that they have a good absorption capacity for DNA and myoglobin over 24 h, after application of a magnetic field. The realization of magnetic virus-shaped {Mo72Fe30}/Mag-Surf spheres may open possibilities for designing other functional nanoparticles, allowing effective control over the delivery/separation of biomolecules
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a Surface-Active Agents
|2 NLM
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|a DNA
|2 NLM
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|a 9007-49-2
|2 NLM
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| 700 |
1 |
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|a Sun, Hong
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Wang, Yitong
|e verfasserin
|4 aut
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| 700 |
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|a Eastoe, Julian
|e verfasserin
|4 aut
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| 700 |
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|a Dong, Shuli
|e verfasserin
|4 aut
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|a Hao, Jingcheng
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1992
|g 34(2018), 24 vom: 19. Juni, Seite 7171-7179
|w (DE-627)NLM098181009
|x 1520-5827
|7 nnns
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| 773 |
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|g volume:34
|g year:2018
|g number:24
|g day:19
|g month:06
|g pages:7171-7179
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|u http://dx.doi.org/10.1021/acs.langmuir.8b01445
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