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20231225035712.0 |
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231225s2018 xx |||||o 00| ||eng c |
| 024 |
7 |
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|a 10.1002/adma.201707442
|2 doi
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|a pubmed24n0943.xml
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|a (DE-627)NLM283118709
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|a (NLM)29663538
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|a DE-627
|b ger
|c DE-627
|e rakwb
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| 041 |
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|a eng
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| 100 |
1 |
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|a Tai, Li-Chia
|e verfasserin
|4 aut
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| 245 |
1 |
0 |
|a Methylxanthine Drug Monitoring with Wearable Sweat Sensors
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| 264 |
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1 |
|c 2018
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| 336 |
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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| 338 |
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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| 500 |
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|a Date Completed 07.03.2019
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|a Date Revised 30.09.2020
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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|a Drug monitoring plays crucial roles in doping control and precision medicine. It helps physicians tailor drug dosage for optimal benefits, track patients' compliance to prescriptions, and understand the complex pharmacokinetics of drugs. Conventional drug tests rely on invasive blood draws. While urine and sweat are attractive alternative biofluids, the state-of-the-art methods require separate sample collection and processing steps and fail to provide real-time information. Here, a wearable platform equipped with an electrochemical differential pulse voltammetry sensing module for drug monitoring is presented. A methylxanthine drug, caffeine, is selected to demonstrate the platform's functionalities. Sweat caffeine levels are monitored under various conditions, such as drug doses and measurement time after drug intake. Elevated sweat caffeine levels upon increasing dosage and confirmable caffeine physiological trends are observed. This work leverages a wearable sweat sensing platform toward noninvasive and continuous point-of-care drug monitoring and management
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|a Journal Article
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|a drug monitoring
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| 650 |
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|a electrochemical sensors
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| 650 |
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4 |
|a flexible electronics
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| 650 |
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4 |
|a wearable biosensors
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| 650 |
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7 |
|a Xanthines
|2 NLM
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| 650 |
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7 |
|a methylxanthine
|2 NLM
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| 650 |
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|a 28109-92-4
|2 NLM
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| 700 |
1 |
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|a Gao, Wei
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Chao, Minghan
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Bariya, Mallika
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Ngo, Quynh P
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Shahpar, Ziba
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Nyein, Hnin Y Y
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Park, Hyejin
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Sun, Junfeng
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Jung, Younsu
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Wu, Eric
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Fahad, Hossain M
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Lien, Der-Hsien
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Ota, Hiroki
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Cho, Gyoujin
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Javey, Ali
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Advanced materials (Deerfield Beach, Fla.)
|d 1998
|g 30(2018), 23 vom: 22. Juni, Seite e1707442
|w (DE-627)NLM098206397
|x 1521-4095
|7 nnns
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| 773 |
1 |
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|g volume:30
|g year:2018
|g number:23
|g day:22
|g month:06
|g pages:e1707442
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| 856 |
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|u http://dx.doi.org/10.1002/adma.201707442
|3 Volltext
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|d 30
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|e 23
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|h e1707442
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