Genome editing using CRISPR/Cas9-targeted mutagenesis An opportunity for yield improvements of crop plants grown under environmental stresses

Genome editing using CRISPR/Cas9-targeted mutagenesis : An opportunity for yield improvements of crop plants grown under environmental stresses

Copyright © 2018 Elsevier Masson SAS. All rights reserved.

Bibliographische Detailangaben
Veröffentlicht in:Plant physiology and biochemistry : PPB. - 1991. - 131(2018) vom: 01. Okt., Seite 31-36
1. Verfasser: Abdelrahman, Mostafa (VerfasserIn)
Weitere Verfasser: Al-Sadi, Abdullah M, Pour-Aboughadareh, Alireza, Burritt, David J, Tran, Lam-Son Phan
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2018
Zugriff auf das übergeordnete Werk:Plant physiology and biochemistry : PPB
Schlagworte:Journal Article Review CRISPR/Cas9 Crops Environmental stresses Genome editing Yields
Beschreibung
Zusammenfassung:Copyright © 2018 Elsevier Masson SAS. All rights reserved.
Developing more crops able to sustainably produce high yields when grown under biotic/abiotic stresses is an important goal, if crop production and food security are to be guaranteed in the face of ever-increasing human population and unpredictable global climatic conditions. However, conventional crop improvement, through random mutagenesis or genetic recombination, is time-consuming and cannot keep pace with increasing food demands. Targeted genome editing (GE) technologies, especially clustered regularly interspaced short palindromic repeats (CRISPR)/(CRISPR)-associated protein 9 (Cas9), have great potential to aid in the breeding of crops that are able to produce high yields under conditions of biotic/abiotic stress. This is due to their high efficiency, accuracy and low risk of off-target effects, compared with conventional random mutagenesis methods. The use of CRISPR/Cas9 system has grown very rapidly in recent years with numerous examples of targeted mutagenesis in crop plants, including gene knockouts, modifications, and the activation and repression of target genes. The potential of the GE approach for crop improvement has been clearly demonstrated. However, the regulation and social acceptance of GE crops still remain a challenge. In this review, we evaluate the recent applications of the CRISPR/Cas9-mediated GE, as a means to produce crop plants with greater resilience to the stressors they encounter when grown under increasing stressful environmental conditions
Beschreibung:Date Completed 22.10.2018
Date Revised 30.09.2020
published: Print-Electronic
Citation Status MEDLINE
ISSN:1873-2690
DOI:10.1016/j.plaphy.2018.03.012