Use of 5-azacytidine in a proof-of-concept study to evaluate the impact of pre-natal and post-natal exposures, as well as within generation persistent DNA methylation changes in Daphnia

Short-term exposures at critical stages of development can lead to delayed adverse effects long after the initial stressor has been removed, a concept referred to as developmental origin of adult disease. This indicates that organisms' phenotypes may epigenetically reflect their past exposure h...

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Veröffentlicht in:Ecotoxicology (London, England). - 1992. - 27(2018), 5 vom: 06. Juli, Seite 556-568
1. Verfasser: Athanasio, Camila Gonçalves (VerfasserIn)
Weitere Verfasser: Sommer, Ulf, Viant, Mark R, Chipman, James Kevin, Mirbahai, Leda
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2018
Zugriff auf das übergeordnete Werk:Ecotoxicology (London, England)
Schlagworte:Journal Article 5-azacytidine DNA methylation Daphnia Epigenetics Postnatal exposure Prenatal exposure Azacitidine M801H13NRU