Injectable Granular Hydrogels with Multifunctional Properties for Biomedical Applications

© 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 30(2018), 20 vom: 24. Mai, Seite e1705912
1. Verfasser: Mealy, Joshua E (VerfasserIn)
Weitere Verfasser: Chung, Jennifer J, Jeong, Heon-Ho, Issadore, David, Lee, Daeyeon, Atluri, Pavan, Burdick, Jason A
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2018
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article biomaterials drug delivery hydrogels microfluidics microgels Hydrogels
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520 |a Injectable hydrogels are useful for numerous biomedical applications, such as to introduce therapeutics into tissues or for 3D printing. To expand the complexity of available injectable hydrogels, shear-thinning and self-healing granular hydrogels are developed from microgels that interact via guest-host chemistry. The microgel properties (e.g., degradation, molecule release) are tailored through their crosslinking chemistry, including degradation in response to proteases. When microgels of varied formulations are mixed, complex release and degradation behaviors are observed, including after injection to permit cellular invasion 
650 4 |a Journal Article 
650 4 |a biomaterials 
650 4 |a drug delivery 
650 4 |a hydrogels 
650 4 |a microfluidics 
650 4 |a microgels 
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700 1 |a Chung, Jennifer J  |e verfasserin  |4 aut 
700 1 |a Jeong, Heon-Ho  |e verfasserin  |4 aut 
700 1 |a Issadore, David  |e verfasserin  |4 aut 
700 1 |a Lee, Daeyeon  |e verfasserin  |4 aut 
700 1 |a Atluri, Pavan  |e verfasserin  |4 aut 
700 1 |a Burdick, Jason A  |e verfasserin  |4 aut 
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