Effects of xylanase supplementation to wheat-based diets on growth performance, nutrient digestibility and gut microbes in weanling pigs

OBJECTIVE: This study was designed to investigate the effects of an Aspergillus sulphureus xylanase expressed in Pichia pastoris on the growth performance, nutrient digestibility and gut microbes in weanling pigs

Bibliographische Detailangaben
Veröffentlicht in:Asian-Australasian journal of animal sciences. - 1998. - 31(2018), 9 vom: 01. Sept., Seite 1491-1499
1. Verfasser: Dong, Bing (VerfasserIn)
Weitere Verfasser: Liu, Shaoshuai, Wang, Chunlin, Cao, Yunhe
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2018
Zugriff auf das übergeordnete Werk:Asian-Australasian journal of animal sciences
Schlagworte:Journal Article 16s rRNA Sequencing Bacterial Community Weanling Pigs Xylanase
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520 |a OBJECTIVE: This study was designed to investigate the effects of an Aspergillus sulphureus xylanase expressed in Pichia pastoris on the growth performance, nutrient digestibility and gut microbes in weanling pigs 
520 |a METHODS: A total of 180 weanling pigs (initial body weights were 8.47±1.40 kg) were assigned randomly to 5 dietary treatments. Each treatment had 6 replicates with 6 pigs per replicate. The experimental diets were wheat based with supplementation of 0, 500, 1,000, 2,000, and 4,000 U xylanase/kg. The experiment lasted 28 days (early phase, d 0 to 14; late phase, d 15 to 28) 
520 |a RESULTS: In the early phase, compared to the control, average daily gain (ADG) was higher for pigs fed diets supplemented with xylanase and there was a quadratic response in ADG (p<0.05). In the entire phase, ADG was higher for the pigs fed 1,000 or 2,000 U/kg xylanase compared to the control (p<0.05). The gain to feed ratio was higher for pigs fed diets supplemented with 1,000 or 2,000 U/kg xylanase compared to the control (p<0.05). Increasing the amount of xylanase improved the apparent total tract digestibility of dry matter, crude protein, neutral detergent fiber, calcium, and phosphorus during both periods (p<0.05). Xylanase supplementation (2,000 U/kg) decreased the proportion of Lachnospiraceae (by 50%) in Firmicutes, but increased Prevotellaceae (by 175%) in Bacteroidetes and almost diminished Enterobacteriaceae (Escherichia-Shigella) in Proteobacteria 
520 |a CONCLUSION: Xylanase supplementation increased growth performance and nutrient digestibility up to 2,000 U/kg. Supplementation of xylanase (2,000 U/kg) decreased the richness of gut bacteria but diminished the growth of harmful pathogenic bacteria, such as Escherichia-Shigella, in the colon 
650 4 |a Journal Article 
650 4 |a 16s rRNA Sequencing 
650 4 |a Bacterial Community Weanling Pigs 
650 4 |a Xylanase 
700 1 |a Liu, Shaoshuai  |e verfasserin  |4 aut 
700 1 |a Wang, Chunlin  |e verfasserin  |4 aut 
700 1 |a Cao, Yunhe  |e verfasserin  |4 aut 
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773 1 8 |g volume:31  |g year:2018  |g number:9  |g day:01  |g month:09  |g pages:1491-1499 
856 4 0 |u http://dx.doi.org/10.5713/ajas.17.0867  |3 Volltext 
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