Facilitated Water Transport through Graphene Oxide Membranes Functionalized with Aquaporin-Mimicking Peptides

© 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 30(2018), 14 vom: 15. Apr., Seite e1705944
1. Verfasser: Lee, Chang Seon (VerfasserIn)
Weitere Verfasser: Choi, Moon-Ki, Hwang, Ye Young, Kim, Hyunki, Kim, Moon Ki, Lee, Yun Jung
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2018
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article biomimetic graphene oxide membranes recognition selectivity
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520 |a Water purification by membranes is widely investigated to address concerns related to the scarcity of clean water. Achieving high flux and rejection simultaneously is a difficult challenge using such membranes because these properties are mutually exclusive in common artificial membranes. Nature has developed a method for this task involving water-channel membrane proteins known as aquaporins. Here, the design and fabrication of graphene oxide (GO)-based membranes with a surface-tethered peptide motif designed to mimic the water-selective filter of natural aquaporins is reported. The short RF8 (RFRFRFRF, where R and F represent arginine and phenylalanine, respectively) octapeptide is a concentrated form of the core component of the Ar/R (aromatic/arginine) water-selective filter in aquaporin. The resulting GO-RF8 shows superior flux and high rejection similar to natural aquaporins. Molecular dynamics simulation reveal the unique configuration of RF8 peptides and the transport of water in GO-RF8 membranes, supporting that RF8 effectively emulates the core function of aquaporins 
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650 4 |a biomimetic 
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700 1 |a Choi, Moon-Ki  |e verfasserin  |4 aut 
700 1 |a Hwang, Ye Young  |e verfasserin  |4 aut 
700 1 |a Kim, Hyunki  |e verfasserin  |4 aut 
700 1 |a Kim, Moon Ki  |e verfasserin  |4 aut 
700 1 |a Lee, Yun Jung  |e verfasserin  |4 aut 
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