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|a 10.1111/vcp.12591
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|a eng
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|a Sapierzyński, Rafał
|e verfasserin
|4 aut
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| 245 |
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|a Carcinosarcoma mimicking a feline injection-site sarcoma in a cat
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| 264 |
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1 |
|c 2018
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| 336 |
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|a Text
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|a ƒaComputermedien
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|a Date Completed 11.10.2018
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|a Date Revised 11.10.2018
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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| 520 |
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|a © 2018 American Society for Veterinary Clinical Pathology.
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|a A 15-year-old spayed female domestic short-haired cat with cutaneous/subcutaneous well-circumscribed, alopecic mass approximately 25 × 30 mm in diameter, localized to the left shoulder region was brought to the veterinary surgery department. Despite the suggestive location and macroscopic appearance, feline injection-site sarcoma was not suspected based on the cytologic examination of fine-needle aspirates. The tumor was surgically resected, and tissue sections were evaluated microscopically. The tumor was found to be nonencapsulated with a distinct border between the neoplastic parenchyma and surrounding connective tissue. The neoplastic tissue consisted of 2 cell populations: elongated to spindle-shaped cells arranged in bands and cords and malignant epithelial-like cells. Both populations showed microscopic features of malignancy. Multinucleate giant cells with irregular cytoplasm were scattered among the neoplastic cells. The spindle-shaped cells strongly expressed vimentin but did not express α-smooth muscle actin (α-SMA) or cytokeratin. Desmin was strongly expressed in about 0-5% of cells. Epithelial-like cells expressed cytokeratin, but not vimentin, desmin, or α-SMA. Multinucleate giant cells expressed vimentin, but did not α-SMA, desmin, or cytokeratin. Based on microscopic observations and IHC results, the final diagnosis was carcinosarcoma with histologic features compatible with feline injection-site sarcoma, but without the clinical aggressiveness of this tumor
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| 650 |
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4 |
|a Case Reports
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| 650 |
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|a Journal Article
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| 650 |
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4 |
|a carcinosarcoma
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| 650 |
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4 |
|a cat
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| 650 |
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4 |
|a cytopathology
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| 650 |
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4 |
|a immunohistochemistry
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| 650 |
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4 |
|a injection-site sarcoma
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|i Enthalten in
|t Veterinary clinical pathology
|d 1975
|g 47(2018), 2 vom: 04. Juni, Seite 297-302
|w (DE-627)NLM098159984
|x 1939-165X
|7 nnns
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| 773 |
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|g volume:47
|g year:2018
|g number:2
|g day:04
|g month:06
|g pages:297-302
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|u http://dx.doi.org/10.1111/vcp.12591
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