Genome-wide association study uncovers a novel QTL allele of AtS40-3 that affects the sex ratio of cyst nematodes in Arabidopsis

Plant-parasitic cyst nematodes are obligate sedentary parasites that infect the roots of a broad range of host plants. Cyst nematodes are sexually dimorphic, but differentiation into male or female is strongly influenced by interactions with the host environment. Female populations typically predomi...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Journal of experimental botany. - 1985. - 69(2018), 7 vom: 24. März, Seite 1805-1814
1. Verfasser: Anwer, Muhammad Arslan (VerfasserIn)
Weitere Verfasser: Anjam, Muhammad Shahzad, Shah, Syed Jehangir, Hasan, M Shamim, Naz, Ali A, Grundler, Florian M W, Siddique, Shahid
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2018
Zugriff auf das übergeordnete Werk:Journal of experimental botany
Schlagworte:Journal Article Research Support, Non-U.S. Gov't
LEADER 01000naa a22002652 4500
001 NLM28038310X
003 DE-627
005 20231225025216.0
007 cr uuu---uuuuu
008 231225s2018 xx |||||o 00| ||eng c
024 7 |a 10.1093/jxb/ery019  |2 doi 
028 5 2 |a pubmed24n0934.xml 
035 |a (DE-627)NLM28038310X 
035 |a (NLM)29378065 
040 |a DE-627  |b ger  |c DE-627  |e rakwb 
041 |a eng 
100 1 |a Anwer, Muhammad Arslan  |e verfasserin  |4 aut 
245 1 0 |a Genome-wide association study uncovers a novel QTL allele of AtS40-3 that affects the sex ratio of cyst nematodes in Arabidopsis 
264 1 |c 2018 
336 |a Text  |b txt  |2 rdacontent 
337 |a ƒaComputermedien  |b c  |2 rdamedia 
338 |a ƒa Online-Ressource  |b cr  |2 rdacarrier 
500 |a Date Completed 15.10.2019 
500 |a Date Revised 15.10.2019 
500 |a published: Print 
500 |a Citation Status MEDLINE 
520 |a Plant-parasitic cyst nematodes are obligate sedentary parasites that infect the roots of a broad range of host plants. Cyst nematodes are sexually dimorphic, but differentiation into male or female is strongly influenced by interactions with the host environment. Female populations typically predominate under favorable conditions, whereas male populations predominate under adverse conditions. Here, we performed a genome-wide association study (GWAS) in an Arabidopsis diversity panel to identify host loci underlying variation in susceptibility to cyst nematode infection. Three different susceptibility parameters were examined, with the aim of providing insights into the infection process, the number of females and males present in the infected plant, and the female-to-male sex ratio. GWAS results suggested that variation in sex ratio is associated with a novel quantitative trait locus allele on chromosome 4. Subsequent candidate genes and functional analyses revealed that a senescence-associated transcription factor, AtS40-3, and PPR may act in combination to influence nematode sex ratio. A detailed molecular characterization revealed that variation in nematode sex ratio was due to the disturbed common promoter of AtS40-3 and PPR genes. Additionally, single nucleotide polymorphisms in the coding sequence of AtS40-3 might contribute to the natural variation in nematode sex ratio 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
700 1 |a Anjam, Muhammad Shahzad  |e verfasserin  |4 aut 
700 1 |a Shah, Syed Jehangir  |e verfasserin  |4 aut 
700 1 |a Hasan, M Shamim  |e verfasserin  |4 aut 
700 1 |a Naz, Ali A  |e verfasserin  |4 aut 
700 1 |a Grundler, Florian M W  |e verfasserin  |4 aut 
700 1 |a Siddique, Shahid  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Journal of experimental botany  |d 1985  |g 69(2018), 7 vom: 24. März, Seite 1805-1814  |w (DE-627)NLM098182706  |x 1460-2431  |7 nnns 
773 1 8 |g volume:69  |g year:2018  |g number:7  |g day:24  |g month:03  |g pages:1805-1814 
856 4 0 |u http://dx.doi.org/10.1093/jxb/ery019  |3 Volltext 
912 |a GBV_USEFLAG_A 
912 |a SYSFLAG_A 
912 |a GBV_NLM 
912 |a GBV_ILN_350 
951 |a AR 
952 |d 69  |j 2018  |e 7  |b 24  |c 03  |h 1805-1814