Thermodynamics of the interaction between antibiotics and extracellular polymeric substances within activated sludge

The removal of antibiotics in biological wastewater treatment plants (WWTPs) has attracted an ever-increasing interest. Extracellular polymeric substances (EPS) play a crucial role in antibiotics' bio-adsorption using activated sludge, but the interaction mechanism between antibiotics and EPS r...

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Veröffentlicht in:Environmental technology. - 1993. - 40(2019), 12 vom: 31. Mai, Seite 1525-1533
1. Verfasser: Zhang, Cheng-Cheng (VerfasserIn)
Weitere Verfasser: Guo, Jin-Song, Chen, You-Peng, Ji, Fang-Ying, Wang, Jing, Yan, Peng, Bai, Yun
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2019
Zugriff auf das übergeordnete Werk:Environmental technology
Schlagworte:Journal Article Extracellular polymeric substances activated sludge antibiotics isothermal titration calorimetry thermodynamics Anti-Bacterial Agents Sewage Waste Water
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520 |a The removal of antibiotics in biological wastewater treatment plants (WWTPs) has attracted an ever-increasing interest. Extracellular polymeric substances (EPS) play a crucial role in antibiotics' bio-adsorption using activated sludge, but the interaction mechanism between antibiotics and EPS remains unclear. In this study, the thermodynamics of interactions between EPS and antibiotics (acetaminophen (ACT) and sulfamethazine (SMZ)) were investigated via isothermal titration calorimetry (ITC). The results show that the extracellular proteins strongly combined with ACT and SMZ, and the binding process depended on entropy driven by the hydrophobic interaction as the main driving force. Environmental conditions have a significant impact on the adsorption performance. Therefore, binding of antibiotics and EPS at different pH and ionic strength were investigated to determine the optimal pH and ionic strength. At the near-neutral condition of pH 6.8, the binding reaction of EPS and antibiotics was the most favorable and the conformational change was the maximal. Ionic strength has an obvious effect on the interaction between EPS and antibiotics. The results of this study provided a better understanding of the interaction between antibiotics and EPS in the WWTPs 
650 4 |a Journal Article 
650 4 |a Extracellular polymeric substances 
650 4 |a activated sludge 
650 4 |a antibiotics 
650 4 |a isothermal titration calorimetry 
650 4 |a thermodynamics 
650 7 |a Anti-Bacterial Agents  |2 NLM 
650 7 |a Sewage  |2 NLM 
650 7 |a Waste Water  |2 NLM 
700 1 |a Guo, Jin-Song  |e verfasserin  |4 aut 
700 1 |a Chen, You-Peng  |e verfasserin  |4 aut 
700 1 |a Ji, Fang-Ying  |e verfasserin  |4 aut 
700 1 |a Wang, Jing  |e verfasserin  |4 aut 
700 1 |a Yan, Peng  |e verfasserin  |4 aut 
700 1 |a Bai, Yun  |e verfasserin  |4 aut 
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773 1 8 |g volume:40  |g year:2019  |g number:12  |g day:31  |g month:05  |g pages:1525-1533 
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