Accelerated Transport of Particles in Confined Channels with a High Roughness Amplitude

We investigate the pressure-driven transport of particles 200 or 300 nm in diameter in shallow microfluidic channels ∼1 μm in height with a bottom wall characterized by a high roughness amplitude of ∼100 nm. This study starts with the description of an assay to generate cracks in hydrophilic thin po...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 34(2018), 4 vom: 30. Jan., Seite 1394-1399
1. Verfasser: Ranchon, Hubert (VerfasserIn)
Weitere Verfasser: Cacheux, Jean, Reig, Benjamin, Liot, Olivier, Teerapanich, Pattamon, Leichlé, Thierry, Joseph, Pierre, Bancaud, Aurélien
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2018
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't
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520 |a We investigate the pressure-driven transport of particles 200 or 300 nm in diameter in shallow microfluidic channels ∼1 μm in height with a bottom wall characterized by a high roughness amplitude of ∼100 nm. This study starts with the description of an assay to generate cracks in hydrophilic thin polymer films together with a structural characterization of these corrugations. Microfluidic chips of variable height are then assembled on top of these rough surfaces, and the transport of particles is assessed by measuring the velocity distribution function for a set of pressure drops. We specifically detect anomalous transport properties for rough surfaces. The maximum particle velocity at the centerline of the channel is comparable to that obtained with smooth surfaces, but the average particle velocity increases nonlinearly with the flow rate. We suggest that the change in the boundary condition at the rough wall is not sufficient to account for our data and that the occurrence of contacts between the particle and the surface transports the particle away from the wall and speeds up its motion. We finally draw perspectives for the separation by field-flow fractionation 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
700 1 |a Cacheux, Jean  |e verfasserin  |4 aut 
700 1 |a Reig, Benjamin  |e verfasserin  |4 aut 
700 1 |a Liot, Olivier  |e verfasserin  |4 aut 
700 1 |a Teerapanich, Pattamon  |e verfasserin  |4 aut 
700 1 |a Leichlé, Thierry  |e verfasserin  |4 aut 
700 1 |a Joseph, Pierre  |e verfasserin  |4 aut 
700 1 |a Bancaud, Aurélien  |e verfasserin  |4 aut 
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