pH/Reduction Dual-Responsive Oxidized Alginate-Doxorubicin (mPEG-OAL-DOX/Cys) Prodrug Nanohydrogels : Effect of Complexation with Cyclodextrins
Novel biocompatible and biodegradable pH/reduction dual-responsive oxidized alginate-doxorubicin (mPEG-OAL-DOX/Cys) prodrug nanohydrogels were designed for tumor-specific intracellular triggered release of anticancer drug DOX by conjugating DOX via acid-labile Schiff base linkage into the PEGylated...
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Bibliographische Detailangaben
| Veröffentlicht in: | Langmuir : the ACS journal of surfaces and colloids. - 1992. - 34(2018), 1 vom: 09. Jan., Seite 416-424
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| 1. Verfasser: |
Zhou, Tingting
(VerfasserIn) |
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| Weitere Verfasser: |
Li, Jiagen,
Jia, Xu,
Zhao, Xubo,
Liu, Peng |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2018
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| Zugriff auf das übergeordnete Werk: | Langmuir : the ACS journal of surfaces and colloids
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| Schlagworte: | Journal Article
Research Support, Non-U.S. Gov't
Alginates
Cyclodextrins
Disulfides
Drug Carriers
Hexuronic Acids
Hydrogels
Prodrugs
Doxorubicin
mehr...
80168379AG
Glucuronic Acid
8A5D83Q4RW |
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