Clustered versus Uniform Display of GALA-Peptides on Carrier Nanoparticles : Enhancing the Permeation of Noncharged Fluid Lipid Membranes

GALA-peptide is a random coil in neutral pH; in acidic pH, it becomes an amphipathic α-helix that aggregates in solution, possibly via its hydrophobic facet that runs along the helix's long axis. In the presence of fluid lipid membranes, the GALA-helix exhibits membrane-active properties that o...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 33(2017), 47 vom: 28. Nov., Seite 13625-13633
1. Verfasser: Locke, Trevan (VerfasserIn)
Weitere Verfasser: Sofou, Stavroula
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2017
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S. Lipid Bilayers Peptides