Diversity of cis-regulatory elements associated with auxin response in Arabidopsis thaliana

© The Author(s) 2017. Published by Oxford University Press on behalf of the Society for Experimental Biology.

Bibliographische Detailangaben
Veröffentlicht in:Journal of experimental botany. - 1985. - 69(2018), 2 vom: 04. Jan., Seite 329-339
1. Verfasser: Cherenkov, Pavel (VerfasserIn)
Weitere Verfasser: Novikova, Daria, Omelyanchuk, Nadya, Levitsky, Victor, Grosse, Ivo, Weijers, Dolf, Mironova, Victoria
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2018
Zugriff auf das übergeordnete Werk:Journal of experimental botany
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Review ARF AuxRE Auxin bHLH bZIP bioinformatics chromatin states mehr... transcriptional regulation Chromatin Indoleacetic Acids Plant Growth Regulators Transcription Factors
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520 |a The phytohormone auxin regulates virtually every developmental process in land plants. This regulation is mediated via de-repression of DNA-binding auxin response factors (ARFs). ARFs bind TGTC-containing auxin response cis-elements (AuxREs), but there is growing evidence that additional cis-elements occur in auxin-responsive regulatory regions. The repertoire of auxin-related cis-elements and their involvement in different modes of auxin response are not yet known. Here we analyze the enrichment of nucleotide hexamers in upstream regions of auxin-responsive genes associated with auxin up- or down-regulation, with early or late response, ARF-binding domains, and with different chromatin states. Intriguingly, hexamers potentially bound by basic helix-loop-helix (bHLH) and basic leucine zipper (bZIP) factors as well as a family of A/T-rich hexamers are more highly enriched in auxin-responsive regions than canonical TGTC-containing AuxREs. We classify and annotate the whole spectrum of enriched hexamers and discuss their patterns of enrichment related to different modes of auxin response 
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650 4 |a bioinformatics 
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650 4 |a transcriptional regulation 
650 7 |a Chromatin  |2 NLM 
650 7 |a Indoleacetic Acids  |2 NLM 
650 7 |a Plant Growth Regulators  |2 NLM 
650 7 |a Transcription Factors  |2 NLM 
700 1 |a Novikova, Daria  |e verfasserin  |4 aut 
700 1 |a Omelyanchuk, Nadya  |e verfasserin  |4 aut 
700 1 |a Levitsky, Victor  |e verfasserin  |4 aut 
700 1 |a Grosse, Ivo  |e verfasserin  |4 aut 
700 1 |a Weijers, Dolf  |e verfasserin  |4 aut 
700 1 |a Mironova, Victoria  |e verfasserin  |4 aut 
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773 1 8 |g volume:69  |g year:2018  |g number:2  |g day:04  |g month:01  |g pages:329-339 
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