Membrane-Fusogen Distance Is Critical for Efficient Coiled-Coil-Peptide-Mediated Liposome Fusion

We have developed a model system for membrane fusion that utilizes lipidated derivatives of a heterodimeric coiled-coil pair dubbed E3 (EIAALEK)3 and K3 (KIAALKE)3. In this system, peptides are conjugated to a lipid anchor via a poly(ethylene glycol) (PEG) spacer, and this contribution studies the i...

Description complète

Détails bibliographiques
Publié dans:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 33(2017), 43 vom: 31. Okt., Seite 12443-12452
Auteur principal: Daudey, Geert A (Auteur)
Autres auteurs: Zope, Harshal R, Voskuhl, Jens, Kros, Alexander, Boyle, Aimee L
Format: Article en ligne
Langue:English
Publié: 2017
Accès à la collection:Langmuir : the ACS journal of surfaces and colloids
Sujets:Journal Article Research Support, Non-U.S. Gov't Lipids Liposomes Peptides