Direct quantification of protein glycan phosphorylation
Phosphorylation is an important post-translational modification (PTM) of proteins and a critical quality attribute for protein therapeutics, especially if it is required for protein function or sub-cellular targeting. Most current methods to quantify phosphorylation are time-consuming, indirect, or...
Ausführliche Beschreibung
Bibliographische Detailangaben
| Veröffentlicht in: | BioTechniques. - 1991. - 63(2017), 3 vom: 01. Sept., Seite 117-123
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| 1. Verfasser: |
Ketcham, Stephanie A
(VerfasserIn) |
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| Weitere Verfasser: |
Ashraf, Muhammad,
Madhavarao, Chikkathur N |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2017
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| Zugriff auf das übergeordnete Werk: | BioTechniques
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| Schlagworte: | Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.
glycosylation
lysosomal enzymes
mannose-6-phosphate
phospho-glycans
phosphorylation
1,3-bis(bis(pyridin-2-ylmethyl)amino)propan-2-ol
Amino Acids
mehr...
Polysaccharides
Pyridines
Glucuronidase
EC 3.2.1.31
Cathepsin D
EC 3.4.23.5 |
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