Centrifugal Extension of Retinal Atrophy in Retinal Pigment Epithelium Tears Secondary to Age-Related Macular Degeneration

Copyright 2017, SLACK Incorporated.

Bibliographische Detailangaben
Veröffentlicht in:Ophthalmic surgery, lasers & imaging retina. - 2013. - 48(2017), 9 vom: 01. Sept., Seite 705-710
1. Verfasser: Capuano, Vittorio (VerfasserIn)
Weitere Verfasser: Farci, Roberta, Miere, Alexandra, Amoroso, Francesca, Bandello, Francesco, Souied, Eric H, Querques, Giuseppe
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2017
Zugriff auf das übergeordnete Werk:Ophthalmic surgery, lasers & imaging retina
Schlagworte:Journal Article
Beschreibung
Zusammenfassung:Copyright 2017, SLACK Incorporated.
BACKGROUND AND OBJECTIVE: To investigate the progression of retinal atrophy in patients with retinal pigment epithelium (RPE) tears secondary to neovascular age-related macular degeneration
PATIENTS AND METHODS: In this retrospective case series, patients were analyzed at two high-volume referral centers. The extension of the areas without RPE was analyzed yearly from baseline to last examination through fundus autofluorescence (FAF) imaging using Region Finder (Heidelberg Engineering, Heidelberg, Germany)
RESULTS: Sixteen eyes of 14 patients were included in the study. Mean follow-up was 70.11 months ± 15.5 months. The average area of atrophy was 6.89 mm2 ± 5.4 mm2 at baseline and 9.21 mm2 ± 7.7 mm2 at the last visit (P < .0001). This accounts for a progression of 0.36 mm2 ± 0.46 mm2/year. In all cases, FAF revealed centrifugal extension of retinal atrophy
CONCLUSIONS: In this series, the area of retinal atrophy enlarged over time. Atrophy enlargement is characterized by centrifugal extension from the base of the tear. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:705-710.]
Beschreibung:Date Completed 05.12.2017
Date Revised 26.07.2018
published: Print
Citation Status MEDLINE
ISSN:2325-8179
DOI:10.3928/23258160-20170829-04