Tautomerization of Thymine Using Ultraviolet Light

Ultraviolet-light-induced changes to the nucleobase thymine deposited onto a MoS2 surface were studied using photoelectron spectroscopy and first-principles calculations. These measurements suggest changes in the molecular structure indicated by changes in core electron binding energies. The experim...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 33(2017), 38 vom: 26. Sept., Seite 9666-9672
1. Verfasser: Vinje, Jakob (VerfasserIn)
Weitere Verfasser: Falck, Merete, Mazzola, Federico, Cooil, Simon Phillip, Koch, Henrik, Høyvik, Ida-Marie, Wells, Justin
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2017
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Thymine QR26YLT7LT
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520 |a Ultraviolet-light-induced changes to the nucleobase thymine deposited onto a MoS2 surface were studied using photoelectron spectroscopy and first-principles calculations. These measurements suggest changes in the molecular structure indicated by changes in core electron binding energies. The experimental work has been interpreted by means of ab initio calculations using coupled cluster singles and doubles (CCSD) linear response theory. Contrary to the expected behavior, i.e., the dimerization of two thymine molecules into a pyrimidine dimer, a shift between two tautomeric forms was observed upon UV-exposure. Exposure to ionizing radiation is known to induce damage in many biological molecules, and the present work gives additional insight into its effects on thymine, the interactions of the molecules, and finally how certain UV photoproducts may be avoided 
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700 1 |a Falck, Merete  |e verfasserin  |4 aut 
700 1 |a Mazzola, Federico  |e verfasserin  |4 aut 
700 1 |a Cooil, Simon Phillip  |e verfasserin  |4 aut 
700 1 |a Koch, Henrik  |e verfasserin  |4 aut 
700 1 |a Høyvik, Ida-Marie  |e verfasserin  |4 aut 
700 1 |a Wells, Justin  |e verfasserin  |4 aut 
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