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231225s2017 xx |||||o 00| ||eng c |
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|a 10.1002/adma.201702945
|2 doi
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|a pubmed24n0915.xml
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|a (NLM)28783216
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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| 100 |
1 |
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|a Kim, Jae-Ho
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Sensitive, Quantitative Naked-Eye Biodetection with Polyhedral Cu Nanoshells
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|c 2017
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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| 338 |
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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|a Date Completed 18.07.2018
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|a Date Revised 01.10.2020
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|a published: Print-Electronic
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|a Citation Status PubMed-not-MEDLINE
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|a © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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|a One of the most heavily used methods in chemical and biological labeling, detection, and imaging is based on silver shell-based enhancement on Au nanoparticles (AuNPs) that is useful for amplifying Rayleigh scattering, colorimetric signal, surface-enhanced Raman scattering, and electrical signal, but poor structural controllability and nonspecific growth of silver shells have limited its applications, especially with respect to signal reproducibility and quantification. Here, a highly specific, well-defined Cu nanopolyhedral shell overgrowth chemistry is developed with the aid of polyethyleneimine (PEI) on AuNPs, and the use of this PEI-mediated Cu polyhedral nanoshell (CuP) chemistry is shown as a means of light-scattering signal enhancement for the development of naked-eye-based highly sensitive and quantitative detections of DNA and viruses. Remarkably, these CuPs are exclusively formed on AuNPs in a controllable manner, with no noticeable nonspecific CuP growth. The findings enable to acquire clearly visible signals without analytic instrumentation, detectable down to 8 × 10-15 m of DNA (anthrax sequence) and 2700 copies of viruses (noroviruses in clinical stool samples) with broad dynamic ranges on archetypal assay platforms. This new method provides a general platform in controlling Cu shell nanostructures and their optical signals, and opens up revenues for highly reliable, quantitative onsite naked-eye biodetection
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|a Journal Article
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|a Cu nanoshells
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|a DNA detection
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| 650 |
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4 |
|a biosensors
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| 650 |
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4 |
|a naked-eye detection
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| 650 |
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4 |
|a norovirus
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| 700 |
1 |
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|a Park, Jeong-Eun
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Lin, Mouhong
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Kim, Sungi
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Kim, Gyeong-Hwan
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Park, SungJun
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Ko, GwangPyo
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Nam, Jwa-Min
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Advanced materials (Deerfield Beach, Fla.)
|d 1998
|g 29(2017), 37 vom: 17. Okt.
|w (DE-627)NLM098206397
|x 1521-4095
|7 nnns
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| 773 |
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|g volume:29
|g year:2017
|g number:37
|g day:17
|g month:10
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|u http://dx.doi.org/10.1002/adma.201702945
|3 Volltext
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