|
|
|
|
| LEADER |
01000naa a22002652 4500 |
| 001 |
NLM274330261 |
| 003 |
DE-627 |
| 005 |
20231225003240.0 |
| 007 |
cr uuu---uuuuu |
| 008 |
231225s2017 xx |||||o 00| ||eng c |
| 024 |
7 |
|
|a 10.1111/nph.14703
|2 doi
|
| 028 |
5 |
2 |
|a pubmed24n0914.xml
|
| 035 |
|
|
|a (DE-627)NLM274330261
|
| 035 |
|
|
|a (NLM)28758689
|
| 040 |
|
|
|a DE-627
|b ger
|c DE-627
|e rakwb
|
| 041 |
|
|
|a eng
|
| 100 |
1 |
|
|a Henriques, Rossana
|e verfasserin
|4 aut
|
| 245 |
1 |
4 |
|a The antiphasic regulatory module comprising CDF5 and its antisense RNA FLORE links the circadian clock to photoperiodic flowering
|
| 264 |
|
1 |
|c 2017
|
| 336 |
|
|
|a Text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a ƒaComputermedien
|b c
|2 rdamedia
|
| 338 |
|
|
|a ƒa Online-Ressource
|b cr
|2 rdacarrier
|
| 500 |
|
|
|a Date Completed 01.06.2018
|
| 500 |
|
|
|a Date Revised 30.09.2020
|
| 500 |
|
|
|a published: Print-Electronic
|
| 500 |
|
|
|a GENBANK: GPL13750, GSE80094
|
| 500 |
|
|
|a CommentIn: New Phytol. 2017 Nov;216(3):626-628. - PMID 29034977
|
| 500 |
|
|
|a Citation Status MEDLINE
|
| 520 |
|
|
|a © 2017 The Authors. New Phytologist © 2017 New Phytologist Trust.
|
| 520 |
|
|
|a Circadian rhythms of gene expression are generated by the combinatorial action of transcriptional and translational feedback loops as well as chromatin remodelling events. Recently, long noncoding RNAs (lncRNAs) that are natural antisense transcripts (NATs) to transcripts encoding central oscillator components were proposed as modulators of core clock function in mammals (Per) and fungi (frq/qrf). Although oscillating lncRNAs exist in plants, their functional characterization is at an initial stage. By screening an Arabidopsis thaliana lncRNA custom-made array we identified CDF5 LONG NONCODING RNA (FLORE), a circadian-regulated lncRNA that is a NAT of CDF5. Quantitative real-time RT-PCR confirmed the circadian regulation of FLORE, whereas GUS-staining and flowering time evaluation were used to determine its biological function. FLORE and CDF5 antiphasic expression reflects mutual inhibition in a similar way to frq/qrf. Moreover, whereas the CDF5 protein delays flowering by directly repressing FT transcription, FLORE promotes it by repressing several CDFs (CDF1, CDF3, CDF5) and increasing FT transcript levels, indicating both cis and trans function. We propose that the CDF5/FLORE NAT pair constitutes an additional circadian regulatory module with conserved (mutual inhibition) and unique (function in trans) features, able to fine-tune its own circadian oscillation, and consequently, adjust the onset of flowering to favourable environmental conditions
|
| 650 |
|
4 |
|a Journal Article
|
| 650 |
|
4 |
|a CYCLING DOF FACTORs (CDFs)
|
| 650 |
|
4 |
|a circadian clock
|
| 650 |
|
4 |
|a flowering time
|
| 650 |
|
4 |
|a long noncoding RNA
|
| 650 |
|
4 |
|a natural antisense transcripts
|
| 650 |
|
7 |
|a Arabidopsis Proteins
|2 NLM
|
| 650 |
|
7 |
|a RNA, Antisense
|2 NLM
|
| 650 |
|
7 |
|a RNA, Long Noncoding
|2 NLM
|
| 650 |
|
7 |
|a RNA, Small Interfering
|2 NLM
|
| 700 |
1 |
|
|a Wang, Huan
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Liu, Jun
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Boix, Marc
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Huang, Li-Fang
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Chua, Nam-Hai
|e verfasserin
|4 aut
|
| 773 |
0 |
8 |
|i Enthalten in
|t The New phytologist
|d 1979
|g 216(2017), 3 vom: 11. Nov., Seite 854-867
|w (DE-627)NLM09818248X
|x 1469-8137
|7 nnns
|
| 773 |
1 |
8 |
|g volume:216
|g year:2017
|g number:3
|g day:11
|g month:11
|g pages:854-867
|
| 856 |
4 |
0 |
|u http://dx.doi.org/10.1111/nph.14703
|3 Volltext
|
| 912 |
|
|
|a GBV_USEFLAG_A
|
| 912 |
|
|
|a SYSFLAG_A
|
| 912 |
|
|
|a GBV_NLM
|
| 912 |
|
|
|a GBV_ILN_350
|
| 951 |
|
|
|a AR
|
| 952 |
|
|
|d 216
|j 2017
|e 3
|b 11
|c 11
|h 854-867
|