Sortilin-Related Receptor Expression in Human Neural Stem Cells Derived from Alzheimer's Disease Patients Carrying the APOE Epsilon 4 Allele
Alzheimer's disease (AD) is the most common form of dementia in the elderly; important risk factors are old age and inheritance of the apolipoprotein E4 (APOE4) allele. Changes in amyloid precursor protein (APP) binding, trafficking, and sorting may be important AD causative factors. Secretase-...
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| Veröffentlicht in: | Neural plasticity. - 1998. - 2017(2017) vom: 28., Seite 1892612
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| 1. Verfasser: |
Zollo, Alen
(VerfasserIn) |
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| Weitere Verfasser: |
Allen, Zoe,
Rasmussen, Helle F,
Iannuzzi, Filomena,
Shi, Yichen,
Larsen, Agnete,
Maier, Thorsten J,
Matrone, Carmela |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2017
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| Zugriff auf das übergeordnete Werk: | Neural plasticity
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| Schlagworte: | Journal Article
Amyloid beta-Peptides
Apolipoprotein E4
LDL-Receptor Related Proteins
Membrane Transport Proteins
SORL1 protein, human |
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